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Inventi Impact - Pharm Tech

Articles

  • Inventi:ppt/23452/17
    FORMULATION APPROACHES TO ENHANCE THE SOLUBILITY OF POORLY SOLUBLE DRUGS
    Ahmed Abd El-Bary, Ibrahim Al Sharabi*

    Sufficient aqueous solubility is an important criterion for a drug candidate for further development. Poor aqueous solubility is usually associated with erratic and low bioavailability. Enhancing aqueous solubility is an essential task during the development process of such compounds. Different formulation approaches have been utilized to overcome this obstacle. Solid dispersions, cyclodextrin complexation, self-emulsifying drug delivery systems, size reduction and mesoporous inorganic carriers are discussed in this review.

    How to Cite this Article
    Ahmed Abd El-Bary, Ibrahim Al Sharabi. Formulation Approaches to Enhance the Solubility of Poorly Soluble Drugs. Inventi Impact: Pharm Tech, 2018(1):1-8, 2018.
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