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Inventi Impact - Pharm Analysis & Quality Assurance

Articles

  • Inventi:ppaqa/27155/18
    FIRST ORDER DERIVATIVE AND AREA UNDER CURVE UV SPECTROSCOPIC METHODS FOR THE ESTIMATION OF CYAMEMAZINE TARTRATE IN BULK AND ITS PHARMACEUTICAL DOSAGE FORM
    Anjaneyulu Vinukonda, K B Chandra Sekhar, B Siva Sai Kiran*, Shaik Muneer, Akkimi Padma

    The present research work focused on development and validation of first order derivative and area under curve (AUC) UV spectroscopic method for the estimation of cyamemazine tartrate in bulk and its pharmaceutical dosage form. The solutions of standard and sample solutions were prepared by ethanol. The calibration curve was observed in the concentration range of 2-12 Micro g/ml for both methods. In first order derivative spectroscopic method absorbance was measured at 259 nm, 289 nm and zero cross-270 nm. In area under curve UV spectroscopic method two wavelengths were selected in the range of 264 nm-276 nm. Other studies of assay, accuracy and precision was carried and statically validated. The described methods suggest utilizing for the routine quality control analysis of analytical laboratories. So, the developed methods were found to be linear, precise and accurate.

    How to Cite this Article
    Anjaneyulu Vinukonda, K B Chandra Sekhar, B Siva Sai Kiran et al. First Order Derivative and Area under Curve UV Spectroscopic Methods for the Estimation of Cyamemazine Tartrate in Bulk and Its Pharmaceutical Dosage Form. Inventi Impact: Pharm Analysis & Quality Assurance, 2019(1):1-4, 2019.
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