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Inventi Impact - Planta Activa

Articles

  • Inventi:ppa/20321/16
    EVALUATION OF ANTHELMINTIC ACTIVITY OF EXTRACTS FROM LEAVES OF RAPHANUS SATIVUS LINN
    Stellaa Robertson*, Thamizharasi, Asha K Rajan

    Raphanus sativus Linn. (Syn: Raphanus caudatus) belonging to the family Brassicaceae, is an annual or biennial bristly herb, cultivated throughout India. Commonly, it is known as radish. The plant is used for the treatment of various ailments like influenza, dysentery, urinary troubles, heart disease, leprosy, cholera, dyspepsia, amenorrhea, paralysis etc. It is known to possess anthelmintic, antitumor, anti-inflammatory, antibacterial and diuretic properties. The present investigation was planned to analyze the anthelmintic activity of different extracts (ethanol, ethyl acetate and chloroform) of leaves of Raphanus sativus. The various doses of extracts were evaluated for their anthelmintic activities on adult Indian earth worms, Pheretima posthumous. All the extracts were able to show anthelmintic activity at 2.5 mg/ml concentration. The activities were comparable with the standard drugs, piperazine citrate and albendazole. All extracts at a dose concentration of 2.5 mg/ml was found to exhibit a better anthelmintic activity than the standard drug albendazole (15 mg/ml) and a lower activity than piperazine citrate (10 mg/ml). As the dose of the extract was increased a gradual increase in its anthelmintic activity was observed. The chloroform and ethanol extract showed better anthelmintic activity in comparison with ethyl acetate extract, from which it could be entitled that these extracts of the species possess anthelmintic activity against common worms and other infections caused due to these parasites.

    How to Cite this Article
    Stellaa Robertson, Thamizharasi, Asha K Rajan. Evaluation of Anthelmintic Activity of Extracts from Leaves of Raphanus sativus Linn. Inventi Impact: Planta Activa, 2017(1):11-13, 2017.
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