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Inventi Rapid - Pharm Tech

Articles

  • Inventi:ppt/31564/20
    A REVIEW ON GENERAL CONSIDERATIONS IN DESIGNING OF BUCCAL MUCOADHESIVE DOSAGE FORMS
    V P Argade*, Y R Thombare

    Among novel drug delivery system buccal mucoadhesive system offers certain unique advantages for the drugs which cannot be easily administered by oral or intravenous route due to their ability to adhere and remain on the oral mucosa to release their drug content gradually. Mucoadhesion is the process where polymers attached to biological substrate, synthetic or natural molecules, to mucus epithelial surface. Buccal mucoadhesive film improve the therapeutic effect of drugs by increasing absorption of drugs through oral mucosa and mucoadhesive polymers increases the contact time with the mucus membranes. This article extensively reviews the brief description of the anatomical structure of oral mucosa, mechanism of drug absorption, aspects of dosage form design, mucoadhesion and mucoadhesive polymers followed by permeation enhancer with its mechanism of actions.

    How to Cite this Article
    V P Argade, Y R Thombare. A Review on General Considerations in Designing of Buccal Mucoadhesive Dosage Forms. Inventi Rapid: Pharm Tech, 2020(3):1-10, 2020.
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