­
­
­
­

Inventi Rapid - Pharm Tech

Articles

  • Inventi:ppt/31568/20
    NANOEMULSIONS: FORMULATION AND APPLICATION IN CANCER THERAPY
    Sanket Kapadne*, Yash Kothari

    Nanoemulsions are the pharmaceutical formulations composed of various particles within a specific size range in nanometers. They have ability to encapsulate the poorly water soluble drug due to their hydrophobic nature. As we know, cancer is the very serious malignancy disorder and until now there is no any specific cure for it. So in order to burst the tumor in cancer and to release the patient from cancer like diseases nanoemulsions can effectively utilized. The main objective of this review is to focus on the various nanoemulsions which can be used in various types of cancer to treat them, also the preparation methods for nanoemulsions for formulation of specific nanoemulsions. Nanoemulsions can effectively used in various types of cancers due to their high lipophilicity, their small droplet size and ability to entrap poorly water soluble drug like paclitaxel (Vit. Enanoemulsion) is a nanoemulsions used in variety of cancers like ovarian cancer, prostate cancer, sometimes in lung cancer. Some other examples are, Curcumin nanoemulsions mostly used in prostrate cancer then CapryolTM-90, Tween 80 (carotenoid nanoemulsions) mostly used in the colon cancer. All of the above examples and their mechanisms showed that nanoemulsions can be easily taken up by tumor cells in malignancy due to their very small droplet size and causes the reduction in the formation of tumor growth also it eliminates the toxicity to healthy cells by cancerous cells and at last they have ability to decrease the migration of cancerous cell toward another/different organs.

    How to Cite this Article
    Sanket Kapadne, Yash Kothari. Nanoemulsions: Formulation and Application in Cancer Therapy. Inventi Rapid: Pharm Tech, 2020(3):1-8, 2020.
    Download Full Text