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Inventi Rapid - Planta Activa

Articles

  • Inventi:ppa/24905/18
    PREPARATION AND CHARACTERIZATION OF ORAL MUCOSAL HERBAL GEL FOR MOUTH ULCER
    Shivam Tayal*, Ashish Jain

    The objective of this work was to develop bioadhesive gel from the herbal extracts (G. glabra and A. catechu) and clove oil for oral mucosal drug delivery with more permeability and less side effects in comparison to other dosage forms for oral mucosal drug delivery such as patches, tablets, ointments, films and powders. Clove oil as oil, triethanolamine as surfactant, propylene glycol as co-surfactant was selected for the preparation of gel. The gel was prepared using different combinations of surfactant, co-surfactant and polymer (Carbopol-934P). Formulations were prepared in different batches (G1 to G4) and the prepared gel was evaluated in terms of appearance, pH, viscosity, spreadibility, drug content and in-vitro drug release. The formulations were shown maximum in-vitro release upto 6 hr and after that the release was constant. Formulation batch G4 was better than other formulations in respect to in-vitro release profile and viscosity.

    How to Cite this Article
    Shivam Tayal, Ashish Jain. Preparation and Characterization of Oral Mucosal Herbal Gel for Mouth Ulcer. Inventi Rapid: Planta Activa, 2018(2):1-4, 2018.
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