­
­
­
­

Inventi Rapid - Novel Excipients

Articles

  • Inventi:pne/54/12
    EVALUATION OF BORASSUS FLABELLIFER STARCH AS AN ALTERNATIVE TABLET EXCIPIENT TO MAIZE STARCH: ASSESSMENT BY PREFORMULATION AND FORMULATION STUDIES
    V Neeharika*, K Latha, B Kusuma Pravallika

    Starch isolated from Borassus flabellifer (Arecaceace) plant was studied as an alternative pharmaceutical excipient to maize starch. The B.flabellifer starch has been evaluated by series of tests as mentioned in Indian Pharmacopoeia before being used for evaluation. It was tested along with maize starch as an alternative excipient by performing battery of preformulation and formulation tests. Preformulation studies like sieve analysis, micrometry, flow properties, moisture content and compatibility studies were done as per recommended procedures. The tablets were prepared by wet and dry granulation using paracetamol and aspirin respectively, with B.flabellifer starch as binder, disintegrant, binder and disintegrant and tablets were evaluated. The results obtained for B.flabellifer starch were comparable with maize starch and the B.flabellifer starch can be used as a pharmaceutical excipient in tablets preparation. Keywords: Borassus flabellifer, starch, binder, excipient and maize starch.

    Download Full Text