­
­
­
­

Inventi Rapid - Animal Models & Cell Assays

Articles

  • Inventi:pac/95/13
    IN-VITRO GLUCOSE UPTAKE ASSAY OF HYDRO METHANOLIC LEAVES EXTRACT OF SYZYGIUM JAMBOS (L) ALSTON IN RAT SKELETAL MUSCLE (L6) CELL LINES
    Yarasu Nagamuni Reddy, P Smana Reddy, M Sadhvi, R Pavan Kumar, R N B S Nareshchandra, V Vinil Kumar

    The purpose of the present study to investigate the Invitro glucose uptake assay of hydromethanolic leaves extract of Syzygium jambos (L) Alston (SJM) on L6 Cell lines. Syzygium jambos (L) Alston Commonly known as rose apple belongs to family Myrtaceae , It is one of the most important medicinal plant in India, Brazil. In Brazil decoction of leaves used for diabetes. Hydromethanolic leaves extract of SJM shows cytotoxic concentration (320µg/ml) in normal cells. The present study we demonstrate that SJM enhance glucose transport in L6 myotubes, the extract possesses significant glucose uptake (%of glucose uptake 113±12.26) compared with standard Insulin (%of glucose uptake 131±17.57) if these effects can be confirmed clinically, SJM Extract may used for prevention of DM. The presented data about hydromethanolic leaf extract of Syzygium jambos (L) Alston having activity such as enhancing glucose uptake in skeletal muscle (L6) cell lines. To conclude this study By using natural plant sources (SJM leaves) we can prevent diabetic complications such as diabetic nephropathy, diabetic retinopathy, and diabetic cancer.

    Download Full Text