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Inventi Impact - Radiology
(Formerly Inventi Rapid/Impact: Imaging)

Patent Watch

  • Dual tip atomic force microscopy probe and method for producing such a probe

    One inventive aspect is related to an atomic force microscopy probe. The probe comprises a tip configuration with two probe tips on one cantilever arm. The probe tips are electrically isolated from each other and of approximately the same height with respect to the cantilever arm. The outer surface of the tip configuration has the shape of a body with a base plane and an apex. The body is divided into two sub-parts by a gap located approximately symmetrically with respect to the apex and approximately perpendicular to the base plane. Another inventive aspect related to methods for producing such an AFM probe.

  • Reconstitute tag-delimited tables in a graphics editing application

    A system and method is described for reconstituting a tag-delimited table structure into a file editable by a graphics editing application, the tag-delimited table structure defining an assembly of visible content, the method comprising parsing the tag-delimited table structure into a plurality of cells, generating a slice region within the file of the graphics editing application corresponding to each of said plurality of cells, calculating a cell boundary for each of the plurality of cells, setting a slice boundary according to the calculated cell boundary, and assembling the visible content into the associated slice regions in the file.

  • Flow reduction hood systems

    Flow reduction hood systems are described which facilitate the visualization of tissue regions through a clear fluid. Such a system may include an imaging hood having one or more layers covering the distal opening and defines one or more apertures which control the infusion and controlled retention of the clearing fluid into the hood. In this manner, the amount of clearing fluid may be limited and the clarity of the imaging of the underlying tissue through the fluid within the hood may be maintained for relatively longer periods of time by inhibiting, delaying, or preventing the infusion of surrounding blood into the viewing field. The aperture size may be controlled to decrease or increase through selective inflation of the membrane or other mechanisms.

  • Systems and methods for generating fluorescent light images

    An imaging system divides image pixels intensities by exposure time to generate image data in units of intensity per time. The imaging system divides a fluorescent light image in intensity per time units by an excitation light image in intensity per time units to provide a quantitative corrected fluorescent light image that is generally invariant to position of an imaging instrument relative to a biological tissue being imaged.

  • Intra-operative molecular imaging

    A system for imaging an abnormal cell and or diseased tissue after topical application of a near infrared protease-specific probe is disclosed. The system includes a protease-specific near infrared (NIRF) imaging probe, means for topically administering the protease-specific probe to a diseased tissue and an imaging device capable of detecting the interaction between the protease-specific NIRF imaging probe and the diseased tissue. A method and surgical procedure are also disclosed.

  • Projection of subsurface structure onto an object's surface

    An imaging system illuminates an object with infrared light to enhance visibility of buried structure beneath the surface of the object, and projects a visible light image of the buried structure onto the surface of the object. The system may include an infrared light source for generating the infrared light and a structure for diffusing the infrared light. The diffusing structure may include one or more layers of diffusing material for diffusing the light. The system further includes a video imaging device for receiving the infrared light reflected from the object and for generating a video image of the buried structure based on the reflected infrared light. The buried structure may be a subcutaneous blood vessel. A calibration procedure is described as well as embodiments for ensuring that the object is maintained in focus at the correct distance.

  • Method for imaging and spectroscopy of tumors and determination of the efficacy of anti-tumor drug therapies

    The present invention relates to methods of passive infrared imaging and dynamic infrared imaging of a tumor or lesion ("DIR") where multiple images are taken before, during and after heating or cooling the tumor or lesion. Patterns of intensity of infrared emission in the infrared image(s) are related to the level of vascularity or metabolic activity of the tumor or lesion, and are used to identify size and shape of the tumor or lesion. The patterns can also be used to determine whether Kaposi's sarcoma lesions, skin cancer lesions and melanomas are active or inactive. Changes in the patterns of infrared emission determined by comparing images taken before, during and after the onset of drug or radiation therapy, are used to assess efficacy of the therapy. The methods can also be used to study tissue affected by angiogenic diseases.

  • Integrated multi-rail imaging system

    The imaging system can comprise a plurality of elongated rails, a scanhead assembly, and a small animal mount assembly. The scanhead assembly is selectively mounted onto a first rail and is constructed and arranged for movement in a linear bi-directional manner along the longitudinal axis of the first rail. The small-animal mount assembly is selectively mounted onto a second rail and is constructed and arranged for movement in a linear bi-directional manner along the longitudinal axis of the second rail. The second rail being mounted relative to the first rail such that the longitudinal axis of the second rail is at an angle to the longitudinal axis of the first rail. Theimaging system can also comprise a needle injection assembly that is selectively mounted onto the third rail and is constructed and arranged for movement in a linear bi-directional manner along the longitudinal axis of the third rail. The third rail being mounted relative to the second rail and the first rail such that the longitudinal axis of the third rail is substantially coaxial to the longitudinal axis of the first rail. Alternatively, the needle injection assembly is mounted onto the first rail, such that the second rail is positioned therebetween the needle injection assembly and the scanhead assembly.

  • Method for the improved display of co-registered 2D-3D images in medical imaging

    The present invention relates to a method, which assists a doctor for instance in orientation in 2D fluoroscopy images. The present invention relates here to a method for displaying co-registered 2D-3D images in medicalimaging, comprising the following steps: determine a 3D or 2D projection which is congruent with a 2D image from a 3D image data set, and overlaid display of the 2D image with the 3D or 2D projection on a monitor, characterized in that the two image parts of the two overlaid images can be adjusted and a shift in the two overlaid images which can be adjusted in at least one direction is enabled.

  • RETRIEVING AND VIEWING MEDICAL IMAGES

    As medical imaging becomes more affordable, and the diversity of diagnostic modalities and therapeutic treatments increase, the amount of data being stored increases, and the problem becomes even more critical. One approach to improve retrieval efficiency of images is to employ semantics to establish a defined set of search and classification terms. However, such semantic systems still require the user to make a selection of the most appropriate term or terms to classify a report or image, and the accuracy of the results are thus dependent on the skill and knowledge of the classifier. According to a first aspect of the invention, a retriever is provided for retrieving a medical image having a searchable attribute, the retriever being configured to interface with a semantic database and an image database, and wherein the searchable attribute is determined by segmenting the medical image, using the anatomical model.

  • TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS

    Transparent ink-jet recording films, compositions, and methods are disclosed. Such films do not exhibit excessive ink drying times. These films exhibit high maximum optical densities and have low haze values. These films are useful for medical imaging.

  • EFFICIENT MAPPING OF TISSUE PROPERTIES FROM UNREGISTERED DATA WITH LOW SIGNAL-TO-NOISE RATIO

    Image processing methods are described that include segmenting boundaries of a region of interest (ROI) and identifying one or more control points, in each of multiple images of the same object, region, or location. The coordinates of each image are transformed from image coordinates into a coordinate frame relative to the control point or points. Image data is resampled and filtered and/or averaged. One or more material properties can be calculated from the resampled and filtered image data and then displayed. Alignment of unregistered image data of multiple images of the same object, region, or location is provided. Applications are described for medical imaging.

  • PET DETECTOR SYSTEM WITH IMPROVED CAPABILITIES FOR QUANTIFICATION

    A nuclear medical imaging system employing radiation detection modules with pixelated scintillator crystals includes a scatter detector (46) configured to detect and label scattered and non-scattered detected radiation events stored in a list mode memory (44). Coincident pairs of both scattered and non-scattered radiation events are detected and the corresponding lines of response (LOR) are determined. A first image representation of the examination region can be reconstructed using the LORs corresponding to both scattered and non-scattered detected radiation events to generate a lower resolution image (60) with good noise statistics. A second higher resolution image (62) of all or a subvolume of the examination region can be generated using LORs that correspond to non-scattered detected radiation events. A quantification processor is configured to extract at least one metric, e.g. volume, count rate, standard uptake value (SUV), or the like, from at least one of the lower resolution image, the higher resolution image, or a combined image (64).

  • METHOD AND DEVICE FOR IMAGE QUALITY ACCREDITATION, HANDS ON CME, AND FOR CONTROL AND ANALYSIS OF ACCREDITATION AT THE ENTERPRISE LEVEL

    A method and device for accreditation of a user on an imaging device is described. The method and device can also be used for providing electronic hands-on continuing medical education credits/hours based on proficiency in generating high-quality images. In addition, other medical imaging devices, such as an ultrasound system--in which image quality is dependent on the user professional's ability--can be upgraded using the disclosed methods and devices, thereby allowing the system to automatically freeze an image if it is best-quality rated. Finally, the disclosed invention provides an analysis of accreditation at the enterprise level.

  • SKIN MARKER

    A skin marker for providing a reference point for a plurality of different medical imaging procedures, said marker incorporating one or more substances having one or more of radiance and/or hydration and/or radiopaque and/or radio luminescent and/or radioactive properties for detection by X-ray and/or Computer Tomography (CT) and/or MRI and/or Ultrasonic scanning processes and/or Positron Emission Tomography (PET), and one or more markings recognisable by an optical imaging process such as 3D surface scanning.

  • SYSTEMS AND METHODS FOR MAKING AND USING A STEERABLE IMAGING SYSTEM CONFIGURED AND ARRANGED FOR INSERTION INTO A PATIENT

    A medical imaging assembly includes a sheath with a lumen. An imaging core is disposed at one end of an imaging core shaft disposed in the lumen. The imaging core shaft bends along a shape memory region when the imaging core is extended from the lumen. The imaging core includes a transducer to image patient tissue, a mirror to redirect acoustic signals between the transducer and patient tissue, and a magnet to drive rotation of the mirror. The magnet is rotatable by a magnetic field generated at the location of the magnet. An imaging core shaft rotator rotates the imaging core shaft such that, when the imaging core is extended from the lumen, rotation of the imaging core shaft causes radial rotation of the imaging core about the sheath. The imaging core shaft rotator includes rotatable imaging core shaft magnets fixedly disposed over a portion of the imaging core shaft.

  • TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS

    Transparent ink-jet recording films, compositions, and methods are disclosed. These films exhibit high maximum optical densities and have low haze values. These films are useful for medical imaging.

  • TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS

    Transparent ink-jet recording films, compositions, and methods are disclosed. These films exhibit high maximum optical densities and have low haze values. Such films are useful for medical imaging.

  • METHOD AND APPARATUS FOR GENERATING VARIABLE RESOLUTION MEDICAL IMAGES

    A hand carried medical imaging device includes a probe configured to acquire raw medical image data, an integrated display, a data memory configured to store the acquired raw medical image data, a back end processor, and a user interface operably coupled to the back end processor configured to receive commands from a user and to instruct the back end processor to display the produced medical image on the integrated display at a first resolution, and to either produce and send either the medical image at the second, higher resolution, to send the acquired raw image data, or both, to the external device, in accordance with the commands from the user.

  • System for image scanning and acquisition with low-dose radiation

    A medical imaging system adaptively acquires anatomical images using a shape adaptive collimator including multiple different portions of X-ray absorbent material automatically adjustable to alter the dimensions of a spatial cross section of an X-ray beam of radiation into a non-rectangular shape, in response to a control signal. The synchronization processor provides a heart rate related synchronization signal derived from a patient cardiac function related parameter. The synchronization signal enables adaptive variation in timing of image acquisition within an individual heart cycle and between successive heart cycles of each individual image frame of multiple sequential image frames. The X-ray image acquisition device uses the shape adaptive collimator for acquiring anatomical images of the region of interest with reduced patient X-ray exposure in response to the synchronization signal. A display processor presents resultant images.

  • TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS

    Transparent ink jet recording films, compositions, and methods are disclosed. These films have improved appearance compared to other similar high optical density films. Such improved appearance films are produced without requiring reduced drying process throughput. These films are useful for medical imaging.

  • TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS

    Transparent ink jet recording films, compositions, and methods are disclosed. These films have improved appearance compared to other similar high optical density films. Such improved appearance films are produced without requiring reduced drying process throughput. These films are useful for medical imaging.

  • Method and Apparatus Regarding Iterative Processes as Pertain to Medical Imaging Information

    A medical-imaging digital-computing platform serves to access a plurality of data objects and to execute an iterative process with respect to these data objects. The data objects themselves each at least generally pertain to portions of the human anatomy and may comprise, for example, both a source data object and a target data object. The platform executes the iterative process to determine at least one of a labeling of a portion of one of the data objects and a geometric relationship between at least portions of at least two of the data objects. This can be done, for example, by automatically employing both a segmentation module and a registration module as steps within the iterative process. This can also comprise determining when to automatically generate an intermediate data object to provide as input to at least one of these modules.

  • Thick targets for transmission x-ray tubes

    This invention relates to the use of thick target materials 50 microns and thicker for an x-ray transmission tube; to possible target material compositions including various elements and their alloys, eutectic alloys, compounds, or intermetallic compounds; and applications for utilizing such thick target transmission x-ray tubes. The target comprises at lease one portion of the target with a thickness of 50 microns or greater. The target can be optionally attached to a substrate end-window essentially transparent to x-rays or be thick enough so that no such substrate is required. Applications include producing a high percentage of monochromatic line mission x-rays of said thick target for use in reduced dose medical imaging and other non-destructive testing applications.

  • SYSTEM AND METHODS FOR PROVIDING INFORMATION RELATED TO A TISSUE REGION OF A SUBJECT

    A system for providing information related to a tissue region of a patient is provided. The system includes a user interface configured for co-displaying medical imaging information of the tissue region and visible light information of the tissue region.

  • METHOD AND SYSTEM FOR IMAGING PATIENTS WITH A PERSONAL MEDICAL DEVICE

    A method and system are provided for detecting the presence of a personal medical device within a patient. A method and system are provided for determining the location and type of the personal medical device as well as other characteristics of the device. A method and system are provided for adapting or customizing a medical imaging procedure to avoid interfering with a personal medical device or to diminish the risk of device interference or malfunction. A method and system are provided for interfacing with health record databases, regulatory databases, medical device databases, or other types of databases to gather information regarding a particular patient's personal medical device and to update said databases with additional information regarding the personal medical device if any is gathered.

  • Medical Imaging Device

    A medical imaging device having a tubular receiving region to receive a patient on a patient couch is proposed. The medical imaging device has a wall at least partially enclosing the receiving region. The medical imaging device features a film disposed on the wall at least partially enclosing the receiving region for generating at least one virtual image. The virtual image refers to a visual mapping of a light-reflecting object and/or an illuminated object.

  • TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS

    Transparent ink jet recording films, compositions, and methods are disclosed. Such films exhibit improved ink-drying and smudging performance. These films exhibit high maximum optical densities and have low haze values. These films are useful for medical imaging.

  • IMAGE PROCESSING METHOD TO DETERMINE SUSPECT REGIONS IN A TISSUE MATRIX, AND USE THEREOF FOR 3D NAVIGATION THROUGH THE TISSUE MATRIX

    A method to generate a final image with a medical imaging system, wherein the final image highlights suspect regions in a tissue matrix and wherein the final image is generated from a first image and from previously acquired images of the tissue matrix is provided. The method comprises: creating a 3D map of suspicion from the previously acquired medical images; generating a 2D map of suspicion by projecting all or part of the 3D map of suspicion onto a plane from a point reproducing the conditions of acquisition of the first image; and generating a final 2D image of the tissue matrix from the first image and/or from the 2D map of suspicion, wherein the final 2D image highlights suspect regions in the tissue matrix.

  • PRETARGETING KIT, METHOD AND AGENTS USED THEREIN

    Described is a pretargeting method, and related kits, for targeted medical imaging and/or therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention involves the use of [4+2] inverse electron demand (retro) Diels-Alder chemistry in providing the coupling between a Pre-targeting Probe and an Effector Probe. To this end one of these probes comprises an electron-deficient tetrazine or other suitable diene, and the other an alkene or alkyne dienohile.

  • Initiating a Scan in a Medical Imaging System

    A method of initiating a scan in a medical imaging device includes detecting a patient-ready signal from a magnetically and radiographically inert communication device and automatically initiating the scan upon detecting the patient-ready signal.

  • PRETARGETING KIT, METHOD AND AGENTS USED THEREIN

    Described is a pretargeting method, and related kits, for targeted medical imaging and/or therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention involves the use of [4+2] inverse electron demand (retro) Diels-Alder chemistry in providing the coupling between a Pre-targeting Probe and an Effector Probe. To this end one of these probes comprises an electron-deficient tetrazine or other suitable diene, and the other a cyclooctene or cyclooctyne.

  • METHOD AND APPARATUS FOR RADIATION RESISTANT IMAGING

    The present invention pertains to an apparatus and method for radiation resistant medical imaging. A scanning beam x-ray source and x-ray detector are used. A detector shield is utilized to shield the x-ray detector from radiation.

  • Method and Apparatus for Acquiring Overlapped Medical Image Slices

    The disclosure describes a technique for medical imaging, referred to herein as the Rapid Interleave Overlap Technique (RIOT), wherein image data is acquired as a plurality of series sequences in a manner that allows for unlimited overlap. RIOT involves interleaving and overlapping 2D image slices of multiple series of image data of the same ROI into a composite data set from which MPR and 3D reconstructions exhibiting excellent resolution properties and crisp image quality can be generated.

  • Apparatus, System, and Method for Non-Convex Prior Image Constrained Compressed Sensing

    Methods, systems, and apparatuses for non-convex prior image constrained compressed sensing are disclosed. In one embodiment, a method is provided for iterative image reconstruction for medical imaging applications which employ a prior image to constrain the reconstruction process allowing the use of fewer high SNR samples or complete but lower SNR samples. The objective function made use of non-convex compressed sensing methods during the iterative reconstruction process. Applications include, but are not limited to radiation dose reduction and fast image acquisition.

  • NONLINEAR RECURSIVE FILTER FOR MEDICAL IMAGE PROCESSING

    A new system and method for medical image processing using a nonlinear recursive filter are disclosed. An input signal including two or more pulses received from a medical imaging system is sampled at a predetermined sampling rate. The maximum magnitude, i.e., peak, and/or the occurrence time of the maximum magnitude of the first pulse of the input signal is/are determined using a nonlinear recursive filter. Predicted magnitude values of the tail of the first pulse can be determined and subtracted from the input signal to correct for pileup before determining the maximum magnitude and/or occurrence time of the next pulses. A medical image can be reconstructed using the determined maximum magnitudes and/or the occurrence times of the maximum magnitudes of the pulses of the input signal. The nonlinear recursive filter can be implemented using one or more look-up tables.

  • Arrangement for Controlling Image Plate and Its Image Information and a Method for Controlling the Arrangement

    A medical imaging system comprises at least an image plate, X-ray device for producing an image of an object on said image plate, and a reading device for reading image information held by the image plate. In connection with the image plate there is a tag containing information for controlling the arrangement in such a manner that when the arrangement has read the information in the tag the arrangement is adapted to perform at least one operation controlled by the information read.

  • CABLE TRANSPORT CARRIER FACILITY AS WELL AS A SYSTEM WITH A MEDICAL IMAGING FACILITY AND A CABLE TRANSPORT CARRIER FACILITY

    A cable transport carrier facility is proposed. The cable transport carrier facility is designed for transport of system cables installed on a medical imaging facility and is able to be installed on the medical imaging facility. The cable transport carrier facility has at least one component which is made at least partly of an organic material.

  • METHOD AND DEVICE FOR RECORDING AND/OR EVALUATING AND DISPLAYING MEDICAL IMAGING DATA RECORDS

    A method is disclosed for recording and displaying medical imaging data records of a body part including fatty tissue. In at least one embodiment, the method includes recording an emission-tomographic data record of the body part; recording a magnetic-resonance imaging data record of the body part using a recording sequence designed such that fatty tissue can be displayed such that it can be distinguished from other types of tissue; identifying regions in the emission-tomographic data record, which regions correspond to fatty tissue, using the magnetic-resonance imaging data record; and modifying the emission-tomographic data record in those regions that correspond to fatty tissue. Further, at least one embodiment relates to a correspondingly designed device for evaluating and displaying medical imaging data records of a body part comprising fatty tissue.

  • METHOD AND SYSTEM FOR MANAGING WORK LISTS FOR MEDICAL IMAGING PROCEDURES

    A work list management method and system is disclosed herewith. The method of maintaining a work list for medical imaging procedures comprises accessing at least one data source by a processor for job information relating to medical imaging procedures; automatically refreshing a work list in regular intervals; the work list being displayed to a clinician performing the imaging procedure; and generating at least one alert based on the new job information in the work list.

  • METHOD AND SYSTEM FOR MANAGING WORK LISTS FOR MEDICAL IMAGING PROCEDURES

    A work list management method and system is disclosed herewith. The method of maintaining a work list for medical imaging procedures comprises accessing at least one data source by a processor for job information relating to medical imaging procedures; automatically refreshing a work list in regular intervals; the work list being displayed to a clinician performing the imaging procedure; and generating at least one alert based on the new job information in the work list.

  • Actively Mode Locked Laser Swept Source for OCT Medical Imaging

    An optical coherence analysis system uses a laser swept source that is constrained to operate in a mode locked condition. This is accomplished by synchronously changing the laser cavity's gain and/or phase based on the round trip travel time of light in the cavity. This improves high speed tuning by taking advantage of frequency shifting mechanisms within the cavity and avoids chaotic laser behavior.

  • DOSE ESTIMATION SERVICE SYSTEM CONFIGURED TO SUPPORT MULTIPLE COMPUTERIZED MEDICAL IMAGINGSCAN PROVIDERS

    Techniques are disclosed for estimating patient radiation exposure during computerized tomography (CT) scans. More specifically, embodiments of the invention provide efficient approaches for generating a suitable patient model used to make such an estimate, to approaches for estimating patient dose by interpolating the results of multiple simulations, and to approaches for a service provider to host a dose estimation service made available to multiple CT scan providers.

  • Medical Imaging Machine and Methods of Use

    A system for medical imaging is provided and includes at least one neutron generator having a neutron generator fuel material and at least one neutron moderator material, a gantry for stationing an imaging subject, a neutron collimator attached to the neutron generator, the collimator disposed between the neutron moderator and the imaging subject, at least one gamma ray camera electrically connected to a processor-based data acquisition system, and software executing on the processor-based data acquisition system from a non-transitory physical medium, the software providing a first function for producing at least one gamma ray spectrum or image, a second function for applying correction factors to the gamma ray spectra or images, and a third function for analyzing the corrected gamma ray spectra or images to process one or more clinically relevant images of one or more targeted or general areas of the imaging subject.

  • GENERATING AN ESTIMATE OF PATIENT RADIATION DOSE FROM MEDICAL IMAGING SCANS

    Techniques are disclosed for estimating patient radiation exposure during computerized tomography (CT) scans. More specifically, embodiments of the invention provide efficient approaches for generating a suitable patient model used to make such an estimate, to approaches for estimating patient dose by interpolating the results of multiple simulations, and to approaches for a service provider to host a dose estimation service made available to multiple CT scan providers.

  • GENERATING A SUITABLE MODEL FOR ESTIMATING PATIENT RADIATION DOSE RESULTING FROM MEDICAL IMAGING SCANS

    Techniques are disclosed for estimating patient radiation exposure during computerized tomography (CT) scans. More specifically, embodiments of the invention provide efficient approaches for generating a suitable patient model used to make such an estimate, to approaches for estimating patient dose by interpolating the results of multiple simulations, and to approaches for a service provider to host a dose estimation service made available to multiple CT scan providers.

  • NANOPHOTONIC SYSTEM FOR OPTICAL DATA AND POWER TRANSMISSION IN MEDICAL IMAGING SYSTEMS

    The present disclosure is directed towards the transmission of data and/or power using nanophotonic elements. For example, in one embodiment, a medical imaging system is provided. The imaging system includes a multiplexed photonic data transfer system having an optical modulator configured to receive an electrical signal representative of a set of data and being operable to modulate a subset of photons defined by time, wavelength, or polarization contained within a beam of light so as to encode the photons with the set of data to produce encoded photons, an optical waveguide interfacing with at least a portion of the optical modulator and configured to transmit the beam of light so as to allow the photons to be modulated by the optical modulator, an optical resonator in communication with the optical waveguide and configured to remove the encoded photons from the beam of light, and a transducer optically connected to the optical resonator and configured to convert the encoded photons into the electrical signal representative of the set of data.

  • Simulation of Medical Imaging

    There is described a method for simulating an imaging process for an organ, the method comprising: retrieving from a memory a 3D volume model of the organ, the 3D volume model describing a 3D structure of the organ and a distribution of density within the 3D structure, the 3D structure representing a surface and internal features of the organ; generating a slice of the 3D model according to a position and an orientation of an imaging device, the slice including a cross-section of the surface and the internal features; rendering an image in accordance with the slice; and displaying the image.

  • USER INTERFACE FOR MEDICAL IMAGING SYSTEM APPLICATIONS

    A user interface configured to display a first set of subject data in a first image workspace on the at least one display. The user interface is further configured to provide for user selection of at least one of a plurality of subject data related to a plurality of image workspaces, attach user comments to and save user comments with the user-selected subject data in the first user-selectable tab after input of user comments, electronically mail the user-selected subject data to one or more designated recipients directly from a first user-selectable tab after input of instructions to electronically mail the user-selected subject data, and automatically open a second image workspace related to the user-selected subject data after user selection of a return link in the first user-selectable tab.

  • MEDICAL IMAGING SYSTEM THAT REDIRECTS HEAT WASTE FOR PATIENT PALLET HEATING

    According to certain embodiments, a medical imaging system includes an imager, a patient pallet, and a heating subsystem. The imager obtains measurement data of a patient. Further, the imager includes at least one electrical component that generates heat. The patient pallet supports the patient to be scanned by the imager. Further, the heating subsystem heats the patient pallet using the heat generated by the at least one electrical component of the imager.

  • System and Method for Automatic Tube Potential Selection for Dose Reduction in Medical Imaging

    A method for CT imaging that utilizes an automatic tube potential selection for individual subjects and diagnostic tasks. The method quantifies the relative radiation dose of different tube potentials for achieving a specific image quality. This allows the selection of a tube potential that provides a reduced radiation dose while still providing CT images of a sufficient quality.

  • Imaging Device and Method of Controlling the Same.

    An imaging device receives from a host image data and commands including a normal command and a real-time command to be processed prior to the normal command. A receiver receives a real-time processing disable command, and a processor processes the image data without processing the real-time command, even if a data sequence identical to the byte stream of the real-time command is included in the image data, after processing the real-time processing disable command. In a method for so controlling an imaging device, a real-time processing disable command is received from the host, after which the real-time processing disable command is processed, after which the image data is processed without processing the real-time command, even if a data sequence identical to the byte stream of the real-time command is included in the image data.

  • Non-Invasive Optical Imaging for Measuring Pulse and Arterial Elasticity in the Brain

    An optical imaging system and a method for generating a report regarding elasticity of arteries in the brain of a subject under test. Light output from the light source of the imaging system non-invasively illuminates at least one blood vessel or region of interest in the brain and, upon the interaction with the vessel, is registered with an optical detector to obtain a shape parameter of a hemodynamic pulse in the vessel. The shape parameter is further correlated to an elasticity parameter of the blood vessel(s) feeding the brain region of interest and presented in a form of report that may be a two- or a three-dimensional image of the parameter across the tested region of the brain.

  • Multiple Beam Spectral Doppler in Medical Diagnostic Ultrasound Imaging.

    Spatially distinct Spectral Doppler information is acquired. Spatially distinct transmit beams are formed at a same time or in parallel. One or more receive beams are formed in response to each transmit beam, providing samples for a plurality of laterally spaced locations. A spectrum is determined for each of a plurality of spatial locations. In another approach, samples are acquired for different regions at different times. The scanning for each region is interleaved based on the anatomic operation. Since spectral estimation relies on a time-continuous series of transmission and reception, the scanning for a region occurs over a sufficient period for spectral estimation before the scanning for a different region occurs. By using anatomic operation, sufficient time is provided for spectral estimation. Due to anatomic operation, different regions are associated with flow at different times.

  • NUCLEAR MEDICINE IMAGING APPARATUS AND NUCLEAR MEDICINE IMAGING SYSTEM

    A PET apparatus includes a clock unit. The clock unit includes: a time measuring unit that measures a time; and a reference time receiving unit that receives a reference time. The PET apparatus also includes a detection time revising unit. By using the reference time received by the reference time receiving unit, the detection time revising unit revises detection times recorded by using the time measured by the time measuring unit. For example, the detection time revising unit revises the detection times by calculating a time error that occurred during an image taking period of a predetermined image taking process by using the time measured by the time measuring unit and the reference time received by the reference time receiving unit and further distributing the calculated time error to each of the detection times recorded during the image taking period.

  • IMAGING APPARATUS FOR DIAGNOSIS AND CONTROL METHOD THEREOF.

    An imaging apparatus for diagnosis and associated control method constructs multiple cross-sectional images in an axial direction inside the body lumen based on line data generated by radially operating a transmitting and receiving unit, and includes a receiving mechanism which receives a count value from a reference position of the transmitting and receiving unit, storage for storing the count value and the line data correlated with each other, an arrangement for constructing a longitudinal-sectional image by aligning the line data based on the count value, a display which displays the longitudinal-sectional image; and a mechanism which reads out line data correlated with the same count value as that of the line data disposed at the position appointed by the user on the displayed longitudinal-sectional image and reconstructing the cross-sectional image.

  • IMAGING SYSTEM.

    A method and apparatus for reconstruction of a region of interest for an object is provided. The reconstruction of the object may be based on chords which may fill a part, all, or more than all of the region of interest. Using chords for reconstruction may allow for reducing data acquired and/or processing for reconstructing a substantially exact image of the ROI. Moreover, various methodologies may be used in reconstructing the image, such as backprojection-filtration, and modified filtration backprojection.

  • IMAGE PROCESSING APPARATUS, IMAGE PROCESSING METHOD, COMPUTER PROGRAM AND IMAGING APPARATUS.

    An image processing apparatus 100 selects one of multiple low-resolution images as a reference image candidate and determines transformation matrices for aligning the other aligning low-resolution images; conducts coordinate-transforming the other low-resolution images with the transformation matrices and plotting the reference image candidate and the coordinate-transformed low-resolution images on to a mapping image to generate a reconfigured image for reference image selection; gives a higher evaluation value to the reference image candidate as the number of pixels of the reference image candidate and the other low-resolution images plotted on the mapping image is larger. This image processing apparatus can select a reference image appropriate for generating a high-quality, high-resolution image from among multiple low-resolution images.

  • MOTION INDEX FOR MEDICAL IMAGING DATA BASED UPON GRANGEAT'S FORMULA.

    Embodiments and processes of computer tomography perform tasks associated with selecting a portion of projection or emission data that contain the least amount of motion based upon a predetermined motion index, a derivative of plane integral (DPI). Other embodiments and processes of computer tomography perform tasks associated with determining an amount of direction-dependent motion in an object based upon a comparison of the DPIs in predetermined directions.

  • DENTAL FLUOROSCOPIC IMAGING SYSTEM

    A dental fluoroscopic imaging system includes a flat panel detector comprising a converter, a plate, a collector, a processing unit, and a transmitter suitable for 2D, intraoral dental fluoroscopy and for 3D extraoral dental fluoroscopy. The converter contains a material capable of transforming low dose radiation received from an emitter after going through the dental examination area into electrical signals. The plate transmits the electric signals to a collector, which amplifies the signals. The processing unit processes the signals into digital images, and the transmitter transfers digital images sequentially to a host computer having software that acquires, processes, transforms, records, freezes, and enhances 2D and 3D images, and compiles videos having video frame rates of between 3 and 100 frames per second. Two dimensional images and video are obtained using a single flat panel detector, while three dimensional images and video are obtained using two flat panel detectors.

  • Method and Apparatus for Compressive Imaging Device

    A new digital image/video camera that directly acquires random projections of the incident light field without first collecting the pixels/voxels. In one preferred embodiment, the camera employs a digital micromirror array to perform optical calculations of linear projections of an image onto pseudorandom binary patterns. Its hallmarks include the ability to obtain an image with only a single detection element while measuring the image/video fewer times than the number of pixels or voxels--this can significantly reduce the computation required for image/video acquisition/encoding. Since the system features a single photon detector, it can also be adapted to image at wavelengths that are currently impossible with conventional CCD and CMOS imagers.

  • IMAGING LENS AND IMAGING APPARATUS.

    An imaging lens includes: a first lens group; a diaphragm; a second lens group having positive refractive power; and a third lens group having negative refractive power, which are arranged in order from an object side, wherein the first lens group is configured by at least one positive lens and one negative lens, wherein the second lens group is configured by a negative lens, a positive lens, and a positive lens in order from the object side, and wherein, when focusing is performed, the second lens group is moved in a direction of an optical axis.

  • ULTRASONIC IMAGING DEVICE AND INFORMATION PROCESSING DEVICE

    Provided is an ultrasonic imaging device that noninvasively measures the stiffness of the cardiac muscle, which is the heart muscle, or intracardiac pressure, which is the blood pressure inside the heart. The ultrasonic imaging device includes: an ultrasonic probe (2) that transmits and receives ultrasonic waves to and from the heart, which is the target organ inside the body; a signal-processing section (15) that processes reflected echo signals received by the ultrasonic probe; a display section (14) that displays the results of signal processing as an image; and an input section (10) for setting a predetermined point on the image displayed on the display section. The signal-processing section (15) includes: a shape-extracting section (152) that perceives information on the shape of the heart from the reflected echo signals; a natural-frequency detecting section (153) that detects the natural frequency of the heart from the reflected echo signals; and a calculating section (154) that calculates the stiffness of the cardiac muscle or the intracardiac pressure, wherein the calculating section (154) accurately calculates the stiffness of the cardiac muscle from the natural frequency of the heart and calculates the intracardiac pressure from the stiffness of the cardiac muscle that has been calculated.

  • Multi-Modality Ultrasound and Radio Frequency System for Imaging Tissue

    This invention provides a dual-modality system for performing characterization and imaging of tissue, tumors, structures, lesions, and ablations under investigation. Specifically, the invention couples ultrasound technology comprising at least two focused ultrasound beams for vibrating target tissues located at the focal point of the ultrasound beams intersection with a radio frequency system for measuring the response of the target tissues. The ultrasound system vibrates the target tissues while the reflected radio frequency energy is transmitted into the target tissues. When reflected, the main carrier tone of the reflected radio frequency energy is cancelled and analysis is performed on the remaining sideband frequencies.

  • Multi-Modality Ultrasound and Radio Frequency System for Imaging Tissue

    This invention provides a dual-modality system for performing characterization and imaging of tissue, tumors, structures, lesions, and ablations under investigation. Specifically, the invention couples ultrasound technology comprising at least two focused ultrasound beams for vibrating target tissues located at the focal point of the ultrasound beams intersection with a radio frequency system for measuring the response of the target tissues. The ultrasound system vibrates the target tissues while the reflected radio frequency energy is transmitted into the target tissues. When reflected, the main carrier tone of the reflected radio frequency energy is cancelled and analysis is performed on the remaining sideband frequencies.

  • ENDOSCOPIC IMAGING DEVICE

    An endoscopic imaging device for endoscopy in a body vessel is disclosed. The device comprises an annular illumination tube comprising an annular illumination fiber for illuminating a body vessel during endoscopy. The device further includes a first imaging tube comprising a first imaging fiber for gross examination and navigation through the body vessel. The first imaging fiber is disposed within the annular illumination tube. The device further comprises a second imaging tube comprising a second imaging fiber for cellular imaging. The second illumination fiber is disposed adjacent the first imaging tube and within the annular illumination tube.

  • CXCR4 ANTAGONISTS FOR IMAGING OF CANCER AND INFLAMMATORY DISORDERS

    The invention provides radiolabeled CXCR4 antagonists, compositions and methods of use for imaging of chemokine CXCR4 receptors and biological conditions associated with the expression of CXCR4 receptors, including cancer, metastasis, and inflammatory disorders.

  • ANALYZING METHOD OF PHASE INFORMATION, ANALYZING PROGRAM OF THE PHASE INFORMATION, STORAGE MEDIUM, AND X-RAY IMAGINGAPPARATUS

    An analyzing method for deriving phase information by analyzing a periodic pattern of moire comprises steps of: subjecting at least a part of the periodic pattern of moire to a windowed Fourier transform by a window function; calculating analytically, based on the moire subjected to the windowed Fourier transform, information of a first spectrum carrying the phase information, and information of a second spectrum superimposed on the information of the first spectrum; and separating the information of the first spectrum from the information of the second spectrum, to derive the phase information.

  • IMAGING DETECTOR AND METHODS FOR IMAGE DETECTION

    An imaging detector includes a scintillator having a scintillator pixel that is configured to emit light. The detector also includes a photosensor that defines a photosensor pixel that is configured to absorb light emitted by the scintillator pixel. A lens is positioned between the scintillator pixel and the photosensor pixel for directing light emitted from the scintillator to the photosensor pixel. The lens is configured to converge light emitted from the scintillator pixel toward the photosensor pixel.

  • METHOD AND APPARATUS FOR IMAGING A SUBJECT USING LOCAL SURFACE COILS

    A Radio Frequency (RF) coil apparatus for generating a Magnetic Resonance (MR) image includes a body adapted to be worn by a subject being scanned, the body comprising an anterior portion, a posterior portion, and a transition portion coupled between the anterior and posterior portions, a first RF receive-only saddle coil including a first coil positioned in the anterior portion and a second coil positioned in the anterior portion, the first RF saddle coil configured to be positioned on the anterior and posterior sides of the subject. An MRI imaging system and method are also described herein

  • PLASTIC SCINTILLATOR, AND SCINTILLATION DETECTOR AND MEDICAL DIAGNOSTIC IMAGING EQUIPMENT USING SAME

    The present invention relates to a scintillation detector, which is largely divided into a scintillator and a photomultiplier, as a constituent element of a medical diagnostic imaging equipment, a scintillator, and a medical diagnostic imaging equipment using the same, and more specifically, to a plastic scintillator, and a scintillation detector and a medical diagnostic imaging equipment using the same wherein a plastic scintillator is provided as a scintillator constituting a scintillation detector of a medical diagnostic imaging equipment instead of a known crystal scintillator, thereby allowing easy processing of a scintillator, improving detection due to various configurations and remarkably reducing processing costs.

  • SOLID-STATE IMAGING DEVICE AND AD CONVERSION METHOD

    A solid-state imaging device includes an imager including pixels arranged in a matrix, and AD converters, each of which is provided in each pixel column and converts a signal voltage read from one of the pixels located in the column to a digital value. Each of the AD converters includes a comparator and a counter section including a counter circuit, which receives a comparison result of the comparator and includes a first DFF for n bits, and a transfer circuit, which includes a second DFF for n bits holding and outputting a count value of the counter circuit. The second DFFs provided in the columns are coupled in series to form a transfer section transferring the signal voltage which has been digitally converted.

  • SYSTEM AND METHOD FOR MULTI-TASKING OF A MEDICAL IMAGING SYSTEM

    A medical imaging system capable of acquiring medical imaging data of a patient includes a console coupled to the system, the console comprising a computer programmed to enable a first user to perform a first task on the system via the console, and enable a second user to perform a second task simultaneously with the first task via a remote device.

  • MONITORING RESPIRATION WITH A THERMAL IMAGING SYSTEM

    What is disclosed is a system and method for monitoring respiration of a subject or subject of interest using a thermal imaging system with single or multiple spectral bands set to a temperature range of a facial region of that person. Temperatures of extremities of the head and face are used to locate facial features in the captured thermal images, i.e., nose and mouth, which are associated with respiration. The RGB signals obtained from the camera are plotted to obtain a respiration pattern. From the respiration pattern, a rate of respiration is obtained. The system includes display and communication interfaces wherein alerts can be activated if the respiration rate falls outside a level of acceptability. The teachings hereof find their uses in an array of devices such as, for example, devices which monitor the respiration of an infant to signal the onset of a respiratory problem or failure.

  • Multi-Modality Ultrasound and Radio Frequency Methodology for Imaging Tissue

    This invention provides a dual-modality system for performing characterization and imaging of tissue, tumors, structures, lesions, and ablations under investigation. Specifically, the invention couples ultrasound technology comprising at least two focused ultrasound beams for vibrating target tissues located at the focal point of the ultrasound beams intersection with a radio frequency system for measuring the response of the target tissues. The ultrasound system vibrates the target tissues while the reflected radio frequency energy is transmitted into the target tissues. When reflected, the main carrier tone of the reflected radio frequency energy is cancelled and analysis is performed on the remaining sideband frequencies

  • Apparatus And Method For Imaging A Medical Instrument

    The invention provides an ultrasound imaging and medical instrument guiding apparatus, a system for acquiring and displaying ultrasound medical images and methods of using the apparatus and system in epidural anesthetic procedure. The apparatus comprises a hand-held ultrasound probe, configured to acquire a volumetric dataset representing a 3-D depiction of a volume; a mount to which the probe is mounted; and a medical instrument guide positionable relative to the ultrasound probe and configured to receive and guide a medical instrument along a propagation axis to a target in a body such that the target and the propagation axis intersect in the volume. The volumetric dataset acquired by the hand-held ultrasound probe comprises information about the medical instrument's position relative to the target in three dimensions and the medical instrument guide has a visible mark from which the depth of the medical instrument insertion along the propagation axis can be referenced.

  • Acoustic Imaging Probe Incorporating Photoacoustic Excitation

    Embodiments of the present invention provide for a photoacoustic imaging probe for use in a photoacoustic imaging system, said probe comprising a cohesive composite acoustic lens incorporating aspheric geometry and exhibiting low or practically no measurable dispersion of acoustic waves constructed of at least one material with a low acoustic impedance and attenuation and a relatively low acoustic velocity and at least one other material with a low acoustic impedance and attenuation and a relatively high acoustic velocity is immersed in preferably a low acoustic velocity and low acoustic impedance fluid. The lens may be designed as an acoustic reflective lens or an acoustic lens incorporating spheric geometry. The lens focuses acoustic waves on an acoustic imager which detects the image. The lens may be considered to be essentially monochromatic.

  • TISSUE IMAGING SYSTEM AND IN VIVO MONITORING METHOD

    An in vivo monitoring method in a laparoscope system is provided. An object image is sequentially created with expression of a surface color of an object in a body cavity. A lock area (specific area) is determined within the object image, the lock area being movable by following motion of the object. A monitor image including a graph of oxygen saturation is generated according to a part image included in the object image and located in the lock area. The monitor image is displayed. Preferably, the oxygen saturation of the lock area is acquired according to two spectral data with respect to wavelengths of which an absorption coefficient is different between oxidized hemoglobin and reduced hemoglobin in data of the object image. The object is constituted by a blood vessel.

  • MEDICAL IMAGE PROCESSING APPARATUS, A MEDICAL IMAGING APPARATUS, AND A METHOD OF PROCESSING MEDICAL IMAGES

    A medical image processing apparatus includes a difference calculator, a removal part, a first statistical processing part, and an estimation part. The difference calculator receives a plurality of medical image data with different imaging positions and obtains the difference between the plurality of medical image data, thereby generating difference image data that represents the difference. The removal part removes the region corresponding to a structure from the difference image data. The first statistical processing part obtains the first standard deviation of pixel values of each pixel of the difference image data with the region corresponding to the structure removed. The estimation part estimates the second standard deviation of the medical image data based on the first standard deviation. The medical image processing apparatus can estimate noise level of medical image data.

  • MULTI-SECTION ALIGNMENT OF IMAGING DATA

    A method of aligning multiple volumetric sections of imaging data is provided. The method comprises aligning a primary volumetric section and a secondary volumetric section which is adjacent to the primary volumetric imaging section, for moving the secondary volumetric section into alignment with the primary volumetric section. A related apparatus for performing the method is also provided.

  • MOTION TRACKING SYSTEM FOR REAL TIME ADAPTIVE IMAGING AND SPECTROSCOPY

    This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or "pose", required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P). This invention also provides for internal calibration and for co-registration over time of the scanner's and tracking system's reference frames to compensate for drift and other inaccuracies that may arise over time.

  • IMAGING APPARATUS AND CONTROL METHOD THEREOF

    An imaging apparatus having an X-ray detector and an image display unit comprises first and second display magnification calculation units and a selection unit. The first display magnification calculation unit receives information of the detected image size, a binning condition and a display frame size, and thereby calculating a first display magnification so as to maximize a display area of the detected image. The second display magnification calculation unit temporarily changes the received binning condition, and by using the temporarily changed binning condition and the received detected image size, and calculates a second display magnification so as to maximize a display area. The selection unit selects the first display magnifications and the temporarily change binning condition if the first display magnification is closer to one and the second display magnification with one.

  • IMAGING APPARATUS AND CONTROL METHOD THEREOF

    An imaging apparatus having an X-ray detector and an image display unit comprises first and second display magnification calculation units and a selection unit. The first display magnification calculation unit receives information of the detected image size, a binning condition and a display frame size, and thereby calculating a first display magnification so as to maximize a display area of the detected image. The second display magnification calculation unit temporarily changes the received binning condition, and by using the temporarily changed binning condition and the received detected image size, and calculates a second display magnification so as to maximize a display area. The selection unit selects the first display magnifications and the temporarily change binning condition if the first display magnification is closer to one and the second display magnification with one.

  • RADIATION IMAGING APPARATUS, AND CONTROL METHOD AND PROGRAM OF THE APPARATUS

    An energy control unit continuously adjusts energy of radiations in one shot emitted by an X-ray irradiation unit. An X-ray detection unit generates a plurality of image data pieces in one shot by detecting the radiations whose energy is continuously adjusted and transmitted through a subject. An image classification unit classifies the plurality of image data pieces generated by the X-ray detection unit into image data generated by the radiations of a high energy side and image data generated by the radiations of a low energy side. An image subtraction unit performs weighting and subtraction on the image data generated by the radiations of the high energy side and the image data generated by the radiations of the low energy side.

  • METHODS AND APPARATUS FOR ULTRASOUND IMAGING

    Actual ultrasound attenuation in tissue is used to calculate gain compensation profiles which are used to create a uniform image. Axial, lateral, elevation gain profiles are used to correct the attenuation and ultrasound variation in each direction. In addition, automatic activation of the automatic gain compensation is described

  • METHOD AND APPARATUS FOR MEDICAL IMAGING USING NEAR-INFRARED OPTICAL TOMOGRAPHY AND FLOURESCENCE TOMOGRAPHY COMBINED WITH ULTRASOUND

    Methods and apparatus for medical imaging using diffusive optical tomography and fluorescent diffusive optical tomography are disclosed. In one embodiment, a method for medical imaging comprises, scanning a tissue volume with near-infrared light to obtain structural parameters, wherein the tissue volume includes a biological entity, scanning the tissue volume with near-infrared light to obtain optical and fluorescence measurements of the scanned volume, segmenting the scanned volume into a first region and a second region, and reconstructing an optical image and a fluorescence image of at least a portion of the scanned volume from the structural parameters and the optical and fluorescence measurements. In another embodiment an apparatus for medical imaging is disclosed.

  • METHOD AND APPARATUS FOR MEDICAL IMAGING USING NEAR-INFRARED OPTICAL TOMOGRAPHY AND FLOURESCENCE TOMOGRAPHY COMBINED WITH ULTRASOUND

    Methods and apparatus for medical imaging using diffusive optical tomography and fluorescent diffusive optical tomography are disclosed. In one embodiment, a method for medical imaging comprises, scanning a tissue volume with near-infrared light to obtain structural parameters, wherein the tissue volume includes a biological entity, scanning the tissue volume with near-infrared light to obtain optical and fluorescence measurements of the scanned volume, segmenting the scanned volume into a first region and a second region, and reconstructing an optical image and a fluorescence image of at least a portion of the scanned volume from the structural parameters and the optical and fluorescence measurements. In another embodiment an apparatus for medical imaging is disclosed.

  • HYPERSPECTRAL IMAGING SYSTEMS AND RELATED METHODS

    Systems and methods for analyzing sublingual microcirculation perfusion and identifying particular nerve tracts. In exemplary embodiments, a digital micro-mirror device is configured to direct a reflected light to a subject area and a controller is configured to alter a parameter of the reflected light.

  • BIMODAL STAR POLYMER ARCHITECTURES AS FLUORESCENT AND MRI IMAGING REAGENTS

    Disclosed are star polymers comprising a polymeric body having a core with a site-isolated chromophore and a plurality of polymer chains emanating from the core; and at least one chelating moiety bonded to at least one polymer chain. Also disclosed are bimodal contrast agents derived from star polymers and further comprising at least one metal chelated by the at least one chelating moiety. Also disclosed are methods of making and using same. Also disclosed are imaging methods employing the disclosed star polymers and/or bimodal contrast agents. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  • CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING

    The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the patient using diagnostic imaging.

  • FILTRATION IMAGING ENHANCEMENT METHOD AND SYSTEM

    In accordance with at least some embodiments of the present disclosure, a process for enhancing a motion-blurred image is presented. The process may include obtaining a prior image based on a plurality of projections, wherein the plurality of projections are computed tomography (CT) images obtained in multiple motion phases. The process may further include performing an enhancement operation based on the prior image to generate an enhanced prior image, generating a plurality of re-projections by forward-projecting the enhanced prior image, generating a plurality of phase-correlated difference images based on the plurality of projections and the plurality of re-projections, filtering the plurality of phase-correlated difference images to generate a plurality of filtered phase-correlated difference images, and generating a plurality of phase-correlated images based on the plurality of filtered phase-correlated difference images and the enhanced prior image.

  • HEAD HOLDER, IMAGING TABLE, AND X-RAY CT APPARATUS

    A head holder for imaging is provided. The head holder includes a base, a head rest configured to receive a head of a subject, the head rest pivotally connected to the base and rotatable about a rotational axis defined through a lower end of the head rest, and a stopper configured to be inserted between the base and the head rest to support the head rest and fix the head rest at a tilt angle that corresponds to an insertion position of the stopper in a body axis direction of the subject.

  • Enhanced resolution imaging systems for digital radiography

    The invention provides methods and apparatus for enhanced PCI and dual-use radiation imaging systems. In one implementation high resolution storage phosphor plate radiation detector (an area detector) is employed for conventional attenuation radiation imaging and/or PCI (including conventional PCI and coded aperture PCI). Slit and slot scan implementations for dual-use systems are introduced. Dedicated single and dual-use slit and slot scan system for conventional attenuation imaging and PCI are described that employ face-on or edge-on detectors. Slit and slot scan systems that employ area detectors are described. Edge-on, structured cell detector designs are described. Applications of edge-on structured cell detectors for CT, Nuclear Medicine, PET, and probe detectors are described

  • DIFFERENTIAL PHASE CONTRAST X-RAY IMAGING SYSTEM AND COMPONENTS

    A differential phase contrast X-ray imaging system includes an X-ray illumination system, a beam splitter arranged in an optical path of the X-ray illumination system, and a detection system arranged in an optical path to detect X-rays after passing through the beam splitter

  • Method For Estimating Effective Atomic Number And Bulk Density Of Rock Samples Using Dual Energy X-Ray Computed Tomographic Imaging

    A method for estimating effective atomic number and bulk density of objects, such as rock samples or well cores, using X-ray computed tomographic imaging techniques is provided. The method effectively compensates for errors in the interpretation of CT scan data and produces bulk densities which have lower residual error compared to actual bulk densities and produces bulk density--effective atomic number trends which are consistent with physical observations.

  • WHITE LIGHT ACHROMATIC GRATING IMAGING POLARIMETER

    White-light snapshot channeled linear imaging (CLI) polarimeters include polarization gratings (PGs) configured to produce a compensated shear between portions of an input light flux in first and second polarization states. The disclosed CLI polarimeters can measure a 2-dimensional distribution of linear Stokes polarization parameters by incorporating two identical PGs placed in series along an optical axis. In some examples, CLI polarimeters are configured to produce linear (S.sub.0, S.sub.1, and S.sub.2) and complete (S.sub.0, S.sub.1, S.sub.2 and S.sub.3) channeled Stokes images.

  • COLOR IMAGING USING TIME-MULTIPLEXED LIGHT SOURCES AND MONOCHROME IMAGE SENSORS WITH MULTI-STORAGE-NODE PIXELS

    Electronic devices may include monochrome image sensors having multi-storage-node image sensor pixels. A multi-storage-node image pixel may be synchronized with artificial light sources of different colors and may include a floating diffusion region and multiple storage regions. The image pixels may be sequentially exposed to each light color and may store charge associated with each color in each of the different storage regions. After exposure, the stored charge may be transferred to the floating diffusion region and subsequently read out using readout circuitry. The image pixel may have one set of storage gates that can perform both storage and transfer functions. Alternatively, the image pixel may have a first set of transfer gates for transferring charge to the storage regions and a second set of transfer gates for transferring charge from the storage regions to the floating diffusion region.

  • NEAR-FIELD MILLIMETER WAVE IMAGING

    Systems and method for near-field millimeter wave imaging are provided, in particular, near-field millimeter wave imaging systems and methods that enable sub-wavelength resolution imaging by scanning objects with sub-wavelength probe elements and capturing and measuring phase and intensity of reflected energy to generate images.

  • END FLANGE FOR A MAGNETIC RESONANCE IMAGING SYSTEM AND METHOD OF MANUFACTURING

    An end flange for a magnetic resonance imaging (MRI) system and method for manufacturing an end flange are provided. One end flange is for a vacuum vessel of the MRI system. The vacuum vessel includes a housing configured to receive therein a magnet assembly and an end flange forming an end of the housing. The flange includes an outer surface, an inner surface, and a core coupled between the outer and inner surfaces, wherein the core has a greater stiffness than the outer surface and the inner surface.

  • SELF CONSISTENT PARALLEL IMAGING WITH TEMPORAL SENSITIVITY ESTIMATION IN REAL-TIME MAGNETIC RESONANCE IMAGING

    Parallel imaging magnetic resonance reconstruction is performed with temporal sensitivity. Rather than estimate the coil sensitivity once for each coil of an array, the coil sensitivity at different times is estimated. The movement of the patient may result in different sensitivities at different times. By using the time varying sensitivity in iterative, self-consistent, non-linear parallel imaging, real-time imaging may be provided with stable artifacts in view of increasing SNR even with higher reduction factors (e.g., 4-6).

  • SELF CONSISTENT PARALLEL IMAGING WITH TEMPORAL SENSITIVITY ESTIMATION IN REAL-TIME MAGNETIC RESONANCE IMAGING

    Parallel imaging magnetic resonance reconstruction is performed with temporal sensitivity. Rather than estimate the coil sensitivity once for each coil of an array, the coil sensitivity at different times is estimated. The movement of the patient may result in different sensitivities at different times. By using the time varying sensitivity in iterative, self-consistent, non-linear parallel imaging, real-time imaging may be provided with stable artifacts in view of increasing SNR even with higher reduction factors (e.g., 4-6).

  • Imaging and Eccentric Atherosclerotic Material Laser Remodeling and/or Ablation Catheter

    Devices, systems, and methods for treating atherosclerotic lesions and other disease states, particularly for treatment of vulnerable plaques, can incorporate optical coherence tomography or other imaging techniques which allow a structure and location of an eccentric plaque to be characterized. Remodeling and/or ablative laser energy can then be selectively and automatically directed to the appropriate plaque structures, often without imposing mechanical trauma to the entire circumference of the lumen wall.

  • Medical and Imaging Nanoclusters

    In one embodiment the present invention discloses a nanocluster or a nanorose composition comprising two or more closely spaced nanoparticles each comprising one or more metals, metal oxides, inorganic substances, or a combination thereof and one or more stabilizers. The stabilizers are in contact with the two or more closely spaced nanoparticles to form a nanocluster composition in which the inorganic weight percentage is greater than 50% and the average size is below 300 nm, and the nanocluster composition has magnetic properties, optical properties or a combination of both.

  • RADIOLABELLED ROTENONE DERIVATIVES AND THEIR USE IN SPECT IMAGING

    The present application discloses a compound of formula (I) or (II): ##STR00001## wherein X is gamma-emitting radionuclide. Also disclosed is a pharmaceutical composition comprising the compound of formula (I), the compound of formula (II), or a mixture thereof, and a physiologically acceptable vehicle and a method of imaging a region in a patient, which includes administering to the patient a diagnostically effective amount of the pharmaceutical composition comprising the compound of formula (I), the compound of formula (II), or a mixture thereof

  • APPARATUS FOR GENERATING DIAGNOSIS IMAGE, MEDICAL IMAGING SYSTEM, AND METHOD FOR PROCESSING IMAGE

    An apparatus for generating a diagnosis image includes a local contrast characteristic calculator configured to calculate local contrast characteristics of radiation image data of a low-energy sub-band from radiation image data generated by radiation having at least two energy bands passing through a subject; a local contrast characteristic applier configured to apply the calculated local contrast characteristics to radiation image data of a full-energy band generated by the radiation having at least two energy bands passing through the subject; and a diagnosis image generator configured to generate a diagnosis image of the subject based on the radiation image data of the full-energy band to which the local contrast characteristics have been applied.

  • X-RAY IMAGING APPARATUS AND METHOD

    An X-ray imaging apparatus and method is provided. An X-ray imaging apparatus includes an X-ray radiation unit configured to radiate a first X-ray and a second X-ray onto a target along a predetermined path, an X-ray detection unit configured to detect the radiated first X-ray and the second X-ray that have passed through the target, and an image data generation unit configured to generate cross-section data that respectively corresponds to the detected first X-ray and the detected second X-ray and represents a predetermined cross-sectional layer of the target. The first X-ray is radiated at a location on the predetermined path that is different from a location on the predetermined path at which the second X-ray is radiated, the first X-ray including X-ray spectra that are different from X-ray spectra of the second X-ray.

  • METHODS FOR ACQUISITION AND DISPLAY IN ULTRASOUND IMAGING

    In general, the invention provides methods for use in the acquisition and display of ultrasound images. In particular, the invention provides methods for displaying ultrasound images using gating of ultrasound acquisition based on subject respiration and/or triggering ultrasound acquisition based on subject ECG. The methods may be employed with any suitable ultrasound system.

  • METHOD AND APPARATUS FOR MEASURING A RATIO OF A VARIABLE IN MEDICAL IMAGING DATA

    In a method and apparatus for measuring a ratio of a variable for assessment in medical imaging data of a subject, a viewable image is generated from source imaging data of the subject. A pair of regions of interest for arrangement on the viewable image is then generated, and a value of the variable for each region of the pair from the source imaging data is determined. The ratio of the two values is then determined from the pair.

  • IMAGING EPILEPSY SOURCES FROM ELECTROPHYSIOLOGICAL MEASUREMENTS

    An example includes a method of imaging brain activity. The method includes receiving signals corresponding to neuronal activity of the brain. The signals are based on a plurality of scalp sensors (110). The method also includes decomposing the signals into spatial and temporal independent components (140). In addition, the method includes localizing a plurality of sources corresponding to the independent components. The method includes generating a spatio-temporal representation of neural activity based on the plurality of sources.

  • IMAGING APPARATUS

    An endoscope system 100 is provided with an optical fiber cable 31 and an electrical cable 32a that transmit pixel information output by a light receiving part 28, an image processor 42 that generates an image based on the pixel information transmitted from the optical fiber cable 31 or the pixel information transmitted from the electrical cable 32a, and a control unit 55 that controls a display unit 71 to display the image generated by the image processor 42, determines whether or not a transmission abnormality is present in the optical fiber cable 31, and selects, as pixel information as a target to be processed by the image processor 42, one of the pixel information transmitted from the optical fiber cable 31 and the pixel information transmitted from the electrical cable 32a depending on a presence of the transmission abnormality in the optical fiber cable 31

  • MARKER IDENTIFICATION DURING GAMMA OR POSITRON IMAGING WITH APPLICATION TO INTERVENTIONAL PROCEDURES

    A method is provided for identifying a marker by co-registering gamma or positron images. The method is capable of being applied during interventional procedures and includes steps for detecting a first two-dimensional image at a first energy level, detecting a second two-dimensional image at a second energy level, displaying simultaneously the first and second two-dimensional images, and selecting display coefficients for the first and second two-dimensional images

  • SOLID STATE IMAGING DEVICE AND FABRICATION METHOD FOR THE SAME

    A solid state imaging device includes a circuit unit formed on a substrate and a photoelectric conversion unit. The photoelectric conversion circuit includes a lower electrode layer placed on the circuit unit, a compound semiconductor thin film of chalcopyrite structure which is placed on the lower electrode layer and functions as an optical absorption layer, and an optical transparent electrode layer placed on the compound semiconductor thin film. The lower electrode layer, the compound semiconductor thin film, and the optical transparent electrode layer are laminated one after another on the circuit unit.

  • SOLID STATE IMAGING DEVICE AND FABRICATION METHOD FOR THE SAME

    A solid state imaging device includes a circuit unit formed on a substrate and a photoelectric conversion unit. The photoelectric conversion circuit includes a lower electrode layer placed on the circuit unit, a compound semiconductor thin film of chalcopyrite structure which is placed on the lower electrode layer and functions as an optical absorption layer, and an optical transparent electrode layer placed on the compound semiconductor thin film. The lower electrode layer, the compound semiconductor thin film, and the optical transparent electrode layer are laminated one after another on the circuit unit.

  • DENTAL IMAGING USING SEGMENTATION AND AN ARCH

    A method and a system for generating an image by obtaining x-ray image data, segmenting the x-ray image data into a first portion above a vertical threshold and a second portion below the vertical threshold. Further, the method and the system include generating an arch for the second plurality of slices, and generating an image based on the arch

  • METHOD AND SYSTEM FOR DETERMINING AN IMAGING DIRECTION AND CALIBRATION OF AN IMAGING APPARATUS

    The present invention relates to a method for determining an imaging direction of an imaging apparatus (10), such as an x-ray apparatus, with a radiation source or an imaging source (12) that emits an imaging beam (14) to an imaging detector (16) along a beam path, comprising the steps of imaging an object (18) from a first direction to obtain a first 2D image; providing 3D reference data, for example a generic or statistical 3D model or an earlier obtained 3D data set, of the imaged object (18); performing a 2D/3D matching of the first 2D image with the 3D reference data to determine a position of an imaging plane (20, 22, 24) of the first 2D image relative to the 3D reference data; and determining the imaging direction of the imaging apparatus (10) relative to the object (18) based on the position of the imaging plane (20, 22, 24) relative to the 3D reference data, as well as to a navigation system for computer-assisted surgery comprising the imaging system of the preceding claim; a tracking system (11), such as optical or IR tracking means; detection devices (13, 15) such as e.g. radiopaque markers (13) detectable by the imaging system and markers (15) detectable by the tracking system (11) attachable to an object (18), wherein the navigation system is adapted to detect a position of the object (18) based on the detection devices (13, 15), in order to generate detection signals and to supply the detection signals to the computer (17) such that the computer can determine point data on the basis of the detection signals received; a calibration object such as a patient body or a phantom bearing detection devices for calibrating the navigation system.

  • METHODS AND APPARATUS FOR ALIGNING SETS OF MEDICAL IMAGING DATA

    In a method and apparatus for aligning two sets of medical imaging data, first and second sets of image data are obtained respectively, using first and second different medical imaging modalities, of an anatomical feature of a subject. For each set, an axis of the anatomical feature and a landmark point for the anatomical feature is determined, and the first and second sets are aligned by comparing the respective axes and landmark points.

  • METHOD AND APPARATUS FOR IDENTIFYING REGIONS OF INTEREST IN MEDICAL IMAGING DATA

    In a method and apparatus for correcting image data from a medical imaging scan of a subject, into which subject a specified amount of an imaging substance has been introduced, a region of the image data, containing an anomalous proportion of the imaging substance introduced, is identified. For the identified region a regional value of a variable in the image data associated with the imaging substance is determined. The regional value is used to determine the proportion of the substance in the region, and the proportion is subtracted from the specified amount of the imaging substance.

  • X RAY SOURCE GRATING STEPPING IMAGING SYSTEM AND IMAGE METHOD

    An X-ray imaging system comprising: an X-ray source, a source grating, a fixed grating module and an X-ray detector, which are successively positioned in the propagation direction of X-ray; an object to be detected is positioned between the source grating and the fixed gating module; said source grating can perform stepping movement in a direction perpendicular to the optical path and grating stripes; wherein the system further comprises a computer workstation for controlling said X-ray source, source grating and X-ray detector so as to perform the following processes: the source grating performs stepping movement in at least one period thereof; at each stepping step, the X-ray source emits X-ray to the object to be detected, and the detector receives the X-ray at the same time; wherein after at least one period of stepping and data acquisition, the light intensity of X-ray at each pixel point on the detector is represented as a light intensity curve; the light intensity curve at each pixel point on the detector is compared with a light intensity curve in the absence of the object to be detected, a pixel value of each pixel point is calculated from change in said light intensity curve; an image of the detected object is reconstructed according to the calculated pixel value.

  • User Targeted Medical Imaging And Information Packaging, Compression And Distribution System

    A computer-based method and system of distributing biological sample data acquired as a digital image of a subject biological sample. The acquired digital image and image capture data are processed according to at least one user. This results in processed image data and capture metadata. The processed image data represents biological sample data of the subject biological sample. A package processing combines the processed image data and capture metadata into a working Package. The method and system enables simultaneous electronic access to the working Package by multiple users, across multiple sectors, in addition to the one user.

  • IMAGING DEVICE AND METHODS OF USING THE SAME

    In one embodiment, a medical device includes a first optical fiber, a second optical fiber, a third optical fiber, and a fourth optical fiber. The first optical fiber is operatively coupled to a first electromagnetic radiation source and is configured to transmit electromagnetic radiation to bodily tissue. The second optical fiber is configured to receive electromagnetic radiation from the first electromagnetic radiation source scattered by the bodily tissue. The third optical fiber is operatively coupled to a second electromagnetic radiation source and is configured to transmit electromagnetic radiation to bodily tissue. The second electromagnetic radiation source is different than the first electromagnetic radiation source. The fourth optical fiber is configured to receive electromagnetic radiation from the second electromagnetic radiation source scattered by the bodily tissue.

  • Visualization of Associated Information in Ultrasound Shear Wave Imaging

    Information associated with shear calculation is also displayed in ultrasound shear wave imaging. More information than just a shear wave image is provided for diagnosis. Information about the quality or variables used to determine shear is also displayed. This additional information may assist the user in determining whether the shear information indicates tissue characteristics or unreliable shear calculation.

  • PORTABLE PET SCANNER FOR IMAGING THE HUMAN BRAIN

    In accordance with at least one disclosed embodiment, an apparatus for use in imaging the human brain by describing the distribution of radiotracers in the human brain is provided. The apparatus may be compact and lightweight enough to be lifted by hand (less than 50 pounds) and affixed to a patient bed. In addition, the apparatus may collect images of both the cerebrum and cerebellum of the patient.

  • WIRELESS INTRA-ORAL IMAGING SYSTEM AND METHOD

    An intra-oral imaging system includes a handheld intra-oral camera in wireless communication with a remote computing device. The computing device includes a display unit and is linked to databases containing historical data for the teeth of a subject. A dentist actuates a touch-sensitive button to prompt capture of images of the subject's teeth, which are wirelessly transmitted to the computing device and graphically displayed. The images generally represent an arrangement and conditions for the teeth. Program modules are executable to identify a current condition of one or more teeth, and to select a prerecorded visual demonstration of a dental procedure from a database based on the identified current condition. Alternatively, the program modules may extrapolate using the current and historical data to predict a future condition and recommend procedures or otherwise alert the subject to potential future procedures. Visual demonstration of the procedures is provided on the display unit.

  • METHODS AND COMPOSITIONS FOR NON-INVASIVE, DYNAMIC IMAGING OF INTESTINAL MOTILITY

    Described are methods and composition for use in non-invasive imaging of intestinal structure and function. These methods can be used to identify, diagnose, assess, monitor and direct therapies for gastrointestinal diseases and disorders. Embodiments of the methods utilize highly sensitive optical imaging and fluorescent spectroscopy techniques to track or monitor packets of organic dye excreted in bile into the intestinal tract to provide quantitative information regarding intestinal propulsion and function.

  • ADAPTIVE IMAGING AND FRAME RATE OPTIMIZING BASED ON REAL-TIME SHAPE SENSING OF MEDICAL INSTRUMENTS

    A system and method for adaptive imaging include a shape sensing system (115, 117) coupled to an interventional device (102) to measure spatial characteristics of the interventional device in a subject. An image module (130) is configured to receive the spatial characteristics and generate one or more control signals in accordance with the spatial characteristics. An imaging device (110) is configured to image the subject in accordance with the control signals.

  • FUNDUS IMAGING APPARATUS AND METHOD

    In order to suppress a load on a subject when a fundus is irradiated with multiple beams, a fundus imaging apparatus for forming an image of a first area in the object, includes: a determination unit for determining a second area other than the first area in the object to be inspected; a detection unit for detecting moving of the object to be inspected on the basis of return light from the second area, which is irradiated with second light; a correction unit for correcting the first area on the basis of the detected moving; and a forming unit for forming an image of the object to be inspected on the basis of the return light from the corrected first area, which is irradiated with the first light.

  • LASER ABLATION ELECTROSPRAY IONIZATION (LAESI) FOR ATMOSPHERIC PRESSURE, IN VIVO, AND IMAGING MASS SPECTROMETRY

    The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI)

  • MOTION COMPENSATION AND PATIENT FEEDBACK IN MEDICAL IMAGING SYSTEMS

    An optical motion sensing system (10) for use in imaging an anatomical structure employs an optical motion sensor (20) including a body contour conforming matrix ("BCCM") (30) and an optical fiber (40). Upon BCCM (30) being adjoined to the anatomical structure, BCCM (30) structurally conforms at least partially to a surface contour of the anatomical structure for reciprocating any motion by the anatomical structure. Optical fiber (40) is at least partially embedded in the BCCM (30) for generating an encoded optical signal (42) indicative of a shape of the optical fiber (40) responsive to any SOS reciprocal motion by the BCCM (30) during an imaging of the anatomical structure. System (10) further employs a motion tracker (50) responsive to encoded optical signal (42) for periodically reconstructing the shape of optical fiber (40) with each change in the shape of optical fiber (40) representing motion by the anatomical structure.

  • SYSTEMS, DEVICES AND METHODS FOR IMAGING AND SURGERY

    Provided herein are devices, systems and methods for treating a vocal fold pathology by forming a substantially planar void below the epithelium of the vocal fold using optical energy. Also provided are devices, systems, and methods for combined imaging and treating of a vocal fold pathology.

  • MAGNETIC RESONANCE IMAGING CONCEPTS

    A method for producing multiple temporal frames of a time-resolved contrast enhanced magnetic resonance angiogram from a subject using an MR contrast agent by repeatedly applying RF pulses and sampling data in the corresponding image k-space along spiral trajectories that start at the k-space center and spiral outward toward the k-space edge.

  • METHODS AND DEVICES FOR GASTROINTESTINAL SURGICAL PROCEDURES USING NEAR INFRARED (nIR) IMAGING TECHNIQUES

    Described herein are methods and devices for performing gastrointestinal surgical procedures using near infrared (nIR) imaging techniques. Described herein are imaging systems, endoscopes, and methods making use of near infrared (nIR) imaging techniques. The imaging systems, endoscopes, and methods can be used, for example, in endoscopic retrograde cholangiopancreatography (ERCP) for visualization of the intraduodenal portion of the bile duct, and in procedures to visualize and to direct treatment of bleeding ulcers, gastrointestinal bleeding, and tumors, for example, a pancreatic mass.

  • METHODS AND APPLICATIONS OF NON-PLANAR IMAGING ARRAYS

    System, devices and methods are presented that provide an imaging array fabrication process method, comprising fabricating an array of semiconductor imaging elements, interconnecting the elements with stretchable interconnections, and transfer printing the array with a pre-strained elastomeric stamp to a secondary non-planar surface.

  • NANOPROBE COMPRISING GOLD COLLOID NANOPARTICLES FOR MULTIMODALITY OPTICAL IMAGING OF CANCER AND TARGETED DRUG DELIVERY FOR CANCER

    The present invention is directed to a nanoparticle loaded with a light sensitive molecule and a method of preparing the nanoparticle, wherein the nanoparticle is a colloidal gold nanoparticle and the light sensitive molecule is non-covalently adsorbed to the surface of the nanoparticle. The present invention is also directed to a nanoprobe comprising the nanoparticle and further comprising a targeting moiety covalently coupled to the surface of the nanoparticle. Additionally, the present invention is directed to an imaging method comprising administering the nanoprobe to a subject and collecting imaging data of the subject or part of the subject with optical multimodality imaging. A method of treating cancer in a subject comprising administering the nanoprobe and performing photodynamic therapy on the subject is further disclosed.

  • N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS

    The present disclosure is directed to compounds, diagnostic agents, and related methods. In some cases, methods for treating patients are provided. More specifically, the disclosure provides compounds, diagnostic agents, and kits for detecting and/or imaging and/or monitoring elastin rich tissues. In addition, the disclosure provides methods of detecting and/or imaging and/or monitoring the presence of coronary plaque, carotid plaque, iliac/femoral plaque, aortic plaque, renal artery plaque, plaque of any arterial vessel, aneurism, vasculitis, other diseases of the arterial wall, and/or damage or structural changes in ligaments, uterus, lungs or skin, as indicated by changes in total vessel wall area, internal lumen size, and exterior arterial perimeter.

  • IDENTIFICATION OF MEDICAL CONCEPTS FOR IMAGING PROTOCOL SELECTION

    A method includes identifying medical concepts in identified patient cases that are missing from medical concepts in first electronically formatted medical information as missing medical concepts, and selecting an imaging protocol for an imaging procedure based on a combination of the medical concepts from the first electronically formatted medical information and the missing medical concepts, and generating a signal indicative of the selected imaging protocol. A method includes identifying at least one of one or more medical concepts as a relevant additional concept, and selecting an imaging protocol for the imaging procedure based on a combination of one or more clinical indications and the relevant additional concept, and generating a signal indicative of the selected imaging protocol.

  • BACTERIAL IMAGING AGENTS AND METHODS OF USING SAME

    The invention provides a family of agents that target bacterial infection, which can be used as imaging agents or therapeutic agents. The agents can be used to image sites of bacterial infection as well as other physiological processes in a subject.

  • SPECTRAL IMAGING

    A method includes analyzing a spectral projection image of a portion of a subject, generating a value quantifying an amount of a target specific contrast material in a region of interest of the spectral projection image, and generating a signal indicative of a presence of the target in response to the value satisfying a predetermined threshold level.

  • IMAGING APPARATUS, SYSTEMS, AND METHODS USEFUL IN INK-BASED DIGITAL PRINTING

    An imager apparatus useful for a digital lithographic printing system includes imaging roll configured to be heated to a first temperature. The imager apparatus may include one or more heating elements for heating the imaging roll to the first temperature within one revolution. The imaging roll may be about the same width as an imaging plate in a cross-process direction, the imaging plate and the imaging roll being configurable for forming an imaging nip in a digital lithographic ink printing system. The imager apparatus may include a solution ejecting mechanism such as a printhead for ejecting fountain solution or water at ambient temperature onto a surface of the imaging roll according digital image data.

  • Medical Imaging Guideline Compliance System

    A system supports medical imaging compliance with guideline and reimbursement requirements using at least one repository and a compliance processor. The at least one repository associates information including, specific reimbursement requirements of a patient insurance company with an imaging protocol compliant with predetermined guidelines for imaging a particular anatomical feature and with a specific type of imaging device and with multiple different steps of the imaging protocol. The compliance processor uses the information in, determining whether a particular imaging protocol for imaging a particular anatomical feature of a particular patient on a particular type of imaging device is compliant with the guidelines and the reimbursement requirements and identifying at least one of, (a) a missing step and (b) an incorrect step, in the particular imaging protocol.

  • DIGITAL LIGHT PROCESSING HYPERSPECTRAL IMAGING APPARATUS

    A hyperspectral imaging system having an optical path. The system including an illumination source adapted to output a light beam, the light beam illuminating a target, a dispersing element arranged in the optical path and adapted to separate the light beam into a plurality of wavelengths, a digital micromirror array adapted to tune the plurality of wavelengths into a spectrum, an optical device having a detector and adapted to collect the spectrum reflected from the target and arranged in the optical path and a processor operatively connected to and adapted to control at least one of: the illumination source; the dispersing element; the digital micromirror array; the optical device; and, the detector, the processor further adapted to output a hyperspectral image of the target. The dispersing element is arranged between the illumination source and the digital micromirror array, the digital micromirror array is arranged to transmit the spectrum to the target and the optical device is arranged in the optical path after the target.

  • MEDICAL DIAGNOSTIC IMAGING APPARATUS

    A medical diagnostic imaging apparatus according to an embodiment comprises: a bed device on which an examinee lies down; a gantry having a tunnel-shaped inner portion into which the bed device moves and inserts a table with which the examinee is in direct contact, and being configured to obtain information on an interior of the examinee by imaging the examinee located in the inner portion; and a control device configured to control drive of the bed device and the gantry. The medical diagnostic imaging apparatus further comprises a multi-degree-of-freedom support mechanism mounted at a position facing the bed device with the gantry interposed in between and configured to support the table based on a control by the control device in accordance with movement of the table.

  • Optimal Respiratory Gating In Medical Imaging

    Methods and computer-readable mediums are provided for obtaining an optimally gated medical image. For example, in one embodiment, a method is provided that acquires medical images in list mode. The method also acquires a respiration correlated signal S(t). Thereafter, a final upper strain threshold value and a final lower strain threshold value pair that has a narrowest interval are selected. The medical images are synchronized with the respiration correlated signal S(t). The synchronized images and signal are used to create an optimally gated medical image. In various embodiments, the disclosed optimal gating can be utilized in PET systems and in other embodiments the disclosed optimal gating can be utilized in SPECT systems. In yet other embodiments, the optimally gated images can be matched to MRI systems and in still other embodiments, the optimally gated images can be matched to CT systems.

  • PROSTATE SPECIFIC ANTIGEN AGENTS AND METHODS OF USING SAME FOR PROSTATE CANCER IMAGING

    The invention provides a family of agents that target the prostate specific antigen, which can be used as imaging agents or therapeutic agents. The agents can be used to image prostate cancer as well as other physiological processes in a subject.

  • RADIOPHARMACEUTICAL IMAGING OF NEURODEGENERATIVE DISEASES

    Methods for simultaneously detecting dementia or cognitive impairment, such as Alzheimer's Disease (AD), Parkinson's Disease (PD), Lewy Body Dementia (LBD) and Vascular Dementia (VaD) in a patient using dual or multiple radiopharmaceutical probes are provided herein.

  • VEIN IMAGING SYSTEMS AND METHODS

    Some embodiments of this disclosure relates to systems and methods for imaging a patient's vasculature. For example, near infrared (NIR) light can be used to illuminate a target area and light that is reflected or scattered from the target area can be used for generate an image of the target area. In some embodiments, the system can be configured such that the image shows the presence, absence, or extent of infiltration or extravasation in the target area. The system can be configured to document that presence, absence, or extend of infiltration or extravasation at an infusion site. In some embodiments, an imaging system can be mounted onto a patient so that the imaging system can monitor an infusion site, and the imaging system can be configured to automatically detect the presence of infiltration or extravasation.

  • SYSTEMS AND METHODS FOR IN VITRO AND IN VIVO IMAGING OF CELLS ON A SUBSTRATE

    Disclosed herein are generally to methods and systems that facilitate imaging of cells on a substrate and more particularly to pre-implantation (in vitro) and post-implantation (in vivo) imaging of cell-seeded substrates implanted in target tissues in the context of stem cell therapy.

  • METHOD FOR QUICKLY AND PRECISELY CALIBRATING MEDICAL IMAGING COMPONENT AFTER POSITION CHANGE

    A method for quickly and precisely calibrating a medical imaging component after position change, comprising: placing a imaging component at a reference position, calibrating, precisely by a first measuring system, the reference position and obtaining a precise calibration value of the reference position; at the same time, performing, by a second measuring system, a second calibration for the reference position of the imaging component and obtaining a reference calibration value of the reference position; measuring, by the second measuring system, the current position of the imaging component and obtaining a reference calibration value of the current position; obtaining a precise calibration value of the current position via calculation based on the precise calibration value of the reference position, the reference calibration value of the reference position, and the reference calibration value of the current position.