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Inventi Rapid - Neonatal & Pediatric Nursing

Patent Watch

  • ELECTRONIC HEALTH RECORD SYSTEM WITH NURSING RECORDS

    An electronic health records system stores medical data and nursing data. The medical data is associated with a physician's findings for an encounter with a patient. The nursing data is associated with nursing care provided to the patient. The electronic health records system generates separate or linked physician and nurse interfaces that can be used to enter and review the medical and nursing data as desired. The electronic health records system also manages nurse scheduling.

  • BED

    Height adjustable beds involve the risk for the patient to fall out of the bed. In order to prevent this to happen, the bed is furnished with a device which observes whether a nursing person is within a proximity zone of the bed. When thenursing person leaves the proximity zone and the bed is adjusted to a height implying potential danger for the person in the bed, a message (sms) is sent to a mobile unit carried by the nursing person. The indication warns the nursingperson, making it possible for him to prevent the potential dangerous situation by height adjustment of the bed to a safe height for leaving the bed. Hereby personal injury is prevented or minimized as much as possible.

  • NURSING PAD CLOTHING LINER

    A nursing pad clothing liner for placing against a woman's breasts to protect from milk leakage.

  • Nipple For An Infant Bottle Assembly And An Infant Bottle Assembly Having Such a Nipple

    A nipple for use with a nursing bottle is provided. The nipple includes a base portion and a bulbous sidewall connected to and extending upward from the base portion. The bulbous sidewall has a height and a maximum width that is larger than said height. The nipple further includes an end portion extending upward from the bulbous sidewall and having an outlet opening therein.

  • Clinical forensic video template: trauma, for mediation and facilitation in personal injury and medical malpractice law

    A medico-legal template process, created by the Medical--Nursing community, that audio-visually demonstrates actual injury and trauma of a patient physically, functionally, mentally, emotionally and psychologically, and it's impact on altering that patient's pre-morbid/baseline activities of daily living, and relationships, both short and long term. The audio-visual record is a patient focused, neutral, medical and nursing assessment and analysis application for the discovery, mediation and litigation components of personal injury and medical malpractice law, and other applicable fields of study. This material is unique and original in that it applies the Nursing Process to the Clinical Forensic Video, it is created by the Medical-Nursing community for the Legal community, and it creates a neutral position within Plaintiff and Defense litigation.

  • DISPOSABLE HOSPITAL CURTAIN SYSTEM WITH SLIDING CURTAIN CARRIERS FOR SNAP-IN INSTALLATION ON EXISTING CEILING TRACKS

    An improved disposable privacy curtain system for use in hospitals, clinics, nursing homes, and other healthcare facilities is disclosed. The disposable privacy curtain system includes a disposable curtain packaged and sold with novel pre-attached sliding carriers affixed to the top edge thereof that are adapted for rapid, snap-in engagement with existing ceiling tracks thereby allowing for rapid removal and replacement of the curtain system. A disposable hospital curtain in accordance with the present invention comprises sheet-like material formed as a generally rectangular panel with vertical fold lines that permit the panel to be drawn between to a compact stowed configuration wherein the curtain is disposed in a pleated and/or folded configuration, and an extended deployed configuration wherein the curtain is extended. In a preferred embodiment, the disposable hospital curtain is fabricated from non-woven polypropylene treated with an antimicrobial agent and a flame retardant.

  • INTEGRATED VERTICAL PLANTING MODULE

    The invention includes a box with a water inlet on top, drainage outlets in the bottom, and multiple nursing cells horizontally and vertically arranged inside. The nursing cells are permanently linked inside the box. Each nursing cell has reservoir grooves in the bottom, and light and air circulation cells around all sides. A slit is placed on adjacent walls of nursing cells in each row, and also in each column, thereby connecting two adjacent nursing cells. The planting module is integrated, ready for use without any assembly required. Light and air circulation cells around nursing cells provide sufficient sunlight for growth of the plants inside. Reservoir grooves in the cell bottom can better keep moisture and nutrients inside. Horizontal and vertical slits in the cell walls provide even and rapid distribution for water that enters the module.

  • Inflatable Mattress Guard

    An inflatable mattress guard is provided. The present invention relates to a mattress guard having a sheet with side pockets on the top surface of the sheet wherein inflatable bladders can be inserted into the pockets and selectively inflated and deflated by the user of the mattress depending on the user's needs and preferences. The invention has application to bed safety devices for hospitals and nursing homes, as well as to general use for toddlers and young children in a home environment.

  • Wet Floor Warning Devices and Methods

    Apparatus and methods for wet floor warnings feature a movable barrier member proximate a doorway at a height elevated above floor level for selective movement between a deployed position in which the barrier member spans at least partially across the doorway and a storage position in which the barrier member is less obstructive to the doorway than in the deployed position for selective display of wet floor warning indicia on the barrier member on a path of sight through the doorway to indicate that the floor surface situated beyond said doorway is wet and may present a slip and fall hazard. The visibility of the warning is improved over floor seated signs, and cleaning personnel going room to room in a large establishment like a hotel, hospital, nursing home, care home, etc. need not transport portable warning signs as they travel the premises.

  • AUTOMATED MEDICATION HANDLING SYSTEM

    Described herein are embodiments of systems and methods for providing an automated medication handling system that can, among other things, single-dose package medications, store and dispense medications in a pharmacy, transport medications to a nursing unit or other remote location, store them at that remote location, and load them into a portable unit carried by a nurse, who may dispense the medication at a bedside.

  • BEVERAGE FOR PREGNANCY & LACTATION

    The invention generally relates to nutrient enhanced beverages which include certain levels of the most current Daily Recommended Intakes of macronutrients and Micronutrients, and the rationale for increased allowances during pregnancy. The beverages of the invention generally comprise one or more macronutrients, vitamins and minerals recommended for consumption by pregnant or lactating women in an amount that is effective for enhancing the nutrition of pregnant and lactating women, and that is not harmful to developing fetuses or breast-feeding babies. In particular, the invention provides high doses of more easily absorbable iron to increase bioavailability of both iron and calcium which normally are not ingested in the needed doses, or are usually ingested via hard to swallow and digest prenatal, iron and calcium pills that can cause stomach cramps, diarrhea, constipation and other gastro-intestinal effects, that often lead to women not getting enough necessary nutrients.

  • Methods of Treating Pediatric Acute Lymphoblastic Leukemia with an Anti-CD22 Immunotoxin

    The present invention provides methods for the treatment of acute lymphoblastic leukemia (ALL) in pediatric patients using an anti-CD22 immunotoxin. The methods disclosed comprise administering to a pediatric patient in need of that treatment an effective dose of a recombinant immunotoxin comprising a variable light (V.sub.L) chain linked to a variable heavy (V.sub.H) which is genetically fused to a therapeutic moiety comprising a Pseudomonas exotoxin A PE38 fragment. The recombinant immunotoxin specifically binds CD22 thereby inhibiting the growth of CD22-expressing (CD22.sup.+) ALL cancer cells.

  • PEDIATRIC COIL ASSEMBLY

    In order to increase the signal to noise ratio, and thus increase the quality of images produced during pediatric MRI, a pediatric RF coil assembly includes a head coil and a flexible body coil in a single dedicated device shaped and sized for a child. The flexible body coil may be operable to at least partially surround and abut the body of the child located on the pediatric RF coil assembly, while the head coil may at least partially surround and abut the head of the child located on the pediatric RF coil assembly. In order to optimize workflow, the child may be positioned on the pediatric RF coil assembly in a first room and moved to a second room including an MRI system after the child is brought to sleep or sedated in the first room. The pediatric RF coil assembly and the child may be moved to the second room using a handle rotatably attached to the pediatric RF coil assembly, and may be positioned on a patient table of the MRI system when the imaging process is to begin.

  • DPP-IV INHIBITORS FOR TREATMENT OF DIABETES IN PEDIATRIC PATIENTS

    The present invention relates to the finding that certain DPP-4 inhibitors are particularly suitable for treating and/or preventing metabolic diseases, particularly diabetes, in paediatric patients.

  • PEDIATRIC TISSUE ILLUMINATOR

    A pediatric tissue illuminator includes a semi-rigid lighting head removably connected to a powered base unit for illuminating an infant's tissues while stabilizing a limb for venipuncture. The lighting head includes a series of LEDs and is placed behind an infant's arm, thereby directing light therethrough for enhanced viewing. A printed circuit board in the lighting head routes electrical conductors to the LEDs. A translucent soft covering is disposed between the printed circuit board and the infant's body. The base unit includes a control circuit for varying the application of electrical power to the lighting head via an electrical cable. The arm board/light head is inexpensive enough to be disposable. Alternatively, a re-useable light head may be used with disposable semi-rigid housings.

  • DRUG DELIVERY SYSTEMS (WAFER) FOR PEDIATRIC USE

    The present invention describes drug delivery compositions in the form of thin water-soluble films (wafers), which contain particles that comprise at least one active ingredient--which is not an estrogen and/or a progestin and/or an alkaline earth metal salt of 5-methyl-(6S)-tetrahydrofolate--and at least one protective agent. The protective agent provides effective taste-masking of the active ingredient due to limited release of the active ingredient in the mouth. The active ingredient is hence not absorbed via the buccal route, but rather via the enteral (per-oral) route. The particles contained in the wafer provided by the present invention have a particle size of below 40 .mu.m thereby resulting in an acceptable sensation in the mouth while dissolving. Such wafers are especially suitable for pediatric use.

  • PEDIATRIC NEBULIZER

    A nebulizer includes a body having an air channel section, medication reservoir and nebulizer outlet configured to be received within an oral cavity of a patient. A nebulizer suction member encloses the body and is configured as an infant pacifier. An air line extends through the air channel section and has a venturi nozzle and at its end configured to form a low pressure mixing chamber. A primary suction line extends from the medication reservoir to the low pressure mixing chamber through which medication is drawn upward and mixed with air passing through the venturi nozzle and nebulized for discharge through the nebulizer outlet.

  • Methods of Treating Pediatric Acute Lymphoblastic Leukemia with an Anti-CD22 Immunotoxin

    The present invention provides methods for the treatment of acute lymphoblastic leukemia (ALL) in pediatric patients using an anti-CD22 immunotoxin. The methods disclosed comprise administering to a pediatric patient in need of that treatment an effective dose of a recombinant immunotoxin comprising a variable light (V.sub.L) chain linked to a variable heavy (V.sub.H) which is genetically fused to a therapeutic moiety comprising a Pseudomonas exotoxin A PE38 fragment. The recombinant immunotoxin specifically binds CD22 thereby inhibiting the growth of CD22-expressing (CD22.sup.+) ALL cancer cells.

  • MODULAR PEDIATRIC PLATFORM

    A modular table is described for supporting a patient during application of a spica cast. In various embodiments, the table is modular, having a support for the patient's upper body and a separate support for the patient's lower body. The supports have coupling members that interface with existing examination or operating tables, or with additional members attached thereto. The coupling members may be placed into features shaped to receive them in one or more spaced-apart positions, or in other embodiments may slide through T-shaped slots or tracks that guide relative alignment of the supports. The tracks for the two supports may be the same or different; straight or curved; and parallel, perpendicular, or skew. Additional fixtures attach to the table or additional members to assist in applying traction to the patient during the application.

  • Compositions and methods of improving the tolerability of daunorubicin when given as orotate salt

    This invention is in the field of anthracycline family of drugs. More particularly, it concerns converting daunorubicin hydrochloride to an orotate salt and providing methods of improving the tolerability of daunorubicin in animals by reducing the adverse effects and toxicity in noncancerous tissues. Daunorubicin orotate provides a safer treatment for specific types of leukemias and neuroblastomas in adults and in pediatric patients.

  • Children Massage Center

    "Children Massage Center" is pediatric massage facility established specially for children from birth to 18 years. Particularly divided facility for different age group where children and parents are introduced to pediatricmassage therapy that utilizes equipment specifically tailored to children, games and toys/tools, and visual stimulants as wall graphics, audio, personal computer etc. Providing massage therapy in such environment significantly increases effectiveness of treatment. Specifically certified and trained pediatric massage therapists will be providing 3 different forms of massage services at the facility for children of all ages. 1. Preventive pediatricmassage service, 2. Therapeutic pediatric massage service, 3. Educational pediatric massage programs for parents and children. The objective is to provide families and their children with currently absent services , the alternative ways to improve their health drug- free and support for families with children with special healthcare needs.

  • FULL NEONATAL CRITICAL CARE EQUIPMENT

    Equipment for the comprehensive care of high-risk newborns that ventilates, incubates, monitors and facilitates medical procedures. The equipment is comprised of: a thermal ring (304) made up of two concentric cylinders joined on the ends by an annular sheet; one or more heating elements (305) between said cylinders encircling the ring, as well as a fan (319) inside the ring; a horizontal cradle (306); a hatch (303A, 303B, 303C) to the ring, located at the front end of the cradle; a cover (307) for the ring, at a point close to the back end of the cradle; a bubble (301) consisting of a space enclosed at the bottom by the cradle, at the top by the thermal ring, to the front by the movable hatch and to the rear by the cover, so that the head of the newborn is located at the front end of the cradle and its feet near the back end; a first water container (308) fed by a first tube (309) connected to a Y-shaped inhalation connector (314); a first valve (313); a second water container (310) fed by a third tube (311), and from which there exits a fourth tube (312) running toward the Y connector (314) fastened to the newborn for ventilation; from the Y connector (314) runs another tube (315) controlled by a second valve (316), in the direction of the first container by way of a second exhalation output tube (317). This equipment has the following novel features: The heating elements (305), circular in shape, located between the two concentric cylinders of the thermal ring, heat the air flow pumped by a fan (319) located between the concentric cylinders. The thermal ring is adjustable and can be slid along the length of the neonatal bubble. A first water container (308), open on top and located outside the bubble (301), simultaneously limits the pressure of the inhalation gas for the newborn, by way of a first tube (309) with a pressure predetermined by its depth for the evacuation of excess gas from the inhalation line; and the pressure of the exhalation gas for the newborn, by way of a second tube (317) that has a pressure predetermined by its depth for the evacuation of the gas coming from the exhalation line, maintaining a positive end-expiratory pressure of the newborn. A second closed water container (310) located inside the bubble (301), which uses the heat of the bubble to humidify the gas entering through an input tube (311) and an output tube (312) that conduct the humidified, heated air to the newborn (302). A gas storage tank (707), inside the thermal ring, which: heats the gas mixture; attenuates or filters the oscillating pressure originating in the compressor; and allows for the continuity of the gas flow delivered by the first valve.

  • METHOD OF MANUFACTURING PEDIATRIC MEDICINE DOSAGE CUP

    A method of manufacturing a dosage cup, comprising the steps of: creating a flavored layer mixture; sterilizing the dosage cup by at least one ozone sterilization device; coating the rim of the dosage cup with the flavored layer mixture to form a flavored layer disposed thereon; and coating the flavored layer with sugar crystals. The ozone sterilization device emits a high-voltage charge to the rim of the cup at an angle in the range of about 0.5 degrees to about 45 degrees. The method may include placing the cup on a conveyor to facilitate the movement of the cup through the high-voltage discharges of the ozone sterilization devices.

  • NOVEL SELF-INFLATING BAG WITH SPECIFIC COMPRESSION MARKS FOR PEDIATRIC AND ADOLESCENT RESUSCITATION

    There is provided a novel self-inflating bag with specific compression marks for pediatric and adolescent resuscitation. The self-inflating bag provides various different range of accurate tidal volume depending on different size or weight of patient by marking compression points on the self-inflating bag.

  • Efficient mucosal vaccination mediated by the neonatal Fc receptor

    The present invention relates to methods and compositions for enhancing delivery of vaccine antigens to the mucosal epithelium, the composition comprising an antigen from an infectious agent fused with an Fc fragment of an immunoglobulin recognized by the neonatal receptors (FcRn). The composition is effective in eliciting a protective long-term memory T cell immune response against infection at a distant mucosal site.

  • REMOTE NON-INVASIVE PARAMETER SENSING SYSTEM AND METHOD

    A remote parameter sensing system is provide that includes a gel sensor, a light source, a detector and a controller 140. The gel sensor is in contact with a surface where the parameter is to be measured, and is preferably a gel that is embedded with a chemical that emits light 160 (via, for example, fluorescence) when it is excited by excitation light from the light source at an appropriate excitation frequency. The chemical properties of the gel sensor are such that at least one characteristic of the emission light (such as, for example, emission intensity) varies as a function of variations in the parameter being measured. The system is particularly suited for use as remote body temperature sensing system in incubators and radiant warmers for infant and neonatal care.

  • Interactive Education System for Teaching Patient Care

    An interactive education system for teaching patient care to a user is described. The system comprises a patient simulator; a virtual instrument for use with the patient simulator in performing patient care activities; means for sensing an interaction between the virtual instrument and the simulator, and means for providing feedback to the user regarding the interaction between the virtual instrument and the simulator. In one aspect, the system includes a maternal simulator, a fetal simulator, and a neonatal simulator.

  • SCGB3A2 AS A GROWTH FACTOR AND ANTI-APOPTOTIC AGENT

    The present disclosure is generally related to methods of using the secretory protein SCGB3A2 for promoting lung development and treating lung disease. Some embodiments are, for example, methods for treating and inhibiting the development of neonatal respiratory distress. Other embodiments are methods of promoting lung development in damaged or diseased lungs. Also disclosed are methods for inhibiting lung damage due to anti-cancer agents.

  • NOVEL CASPASE-2 INHIBITORS

    Novel compounds of formula (I) and slats thereof and pharmaceutical compositions which contain such a compound or salt are useful for inhibiting pro-apoptotic caspase-2 and for preventing and/or treating diseases and injuries where caspase-2 activity is implicated, in particular neonatal brain ischemia.

  • TREATMENT OF SPECIFIC CARDIOVASCULAR CONDITIONS WITH NITRITE

    It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial, for example, to tissues in regions of low oxygen tension. This discovery provides useful treatments to regulate a subject's blood pressure and blood flow, for example, by the administration of nitrite salts. Provided herein are methods of administering a pharmaceutically-acceptable nitrite salt to a subject, for treating, preventing or ameliorating a condition selected from: (a) ischemia-reperfusion injury (e.g., hepatic or cardiac or brain ischemia-reperfusion injury); (b) pulmonary hypertension (e.g., neonatal pulmonary hypertension); or (c) cerebral artery vasospasm.

  • TREATMENT OF SPECIFIC CARDIOVASCULAR CONDITIONS WITH NITRITE

    It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial, for example, to tissues in regions of low oxygen tension. This discovery provides useful treatments to regulate a subject's blood pressure and blood flow, for example, by the administration of nitrite salts. Provided herein are methods of administering a pharmaceutically-acceptable nitrite salt to a subject, for treating, preventing or ameliorating a condition selected from: (a) ischemia-reperfusion injury (e.g., hepatic or cardiac or brain ischemia-reperfusion injury); (b) pulmonary hypertension (e.g., neonatal pulmonary hypertension); or (c) cerebral artery vasospasm.

  • MANUAL AND AUTOMATIC PROBE CALIBRATION

    Embodiments of the present disclosure include an optical probe capable of communicating identification information to a patient monitor in addition to signals indicative of intensities of light after attenuation by body tissue. The identification information may indicate operating wavelengths of light sources, indicate a type of probe, such as, for example, that the probe is an adult probe, a pediatric probe, a neonatal probe, a disposable probe, a reusable probe, or the like. The information could also be utilized for security purposes, such as, for example, to ensure that the probe is configured properly for the oximeter, to indicate that the probe is from an authorized supplier, or the like.

  • SYSTEM AND METHOD OF MONITORING THE PHYSIOLOGICAL CONDITIONS OF A GROUP OF INFANTS

    A system for monitoring the physiological conditions of a plurality of infants in a neonatal intensive care unit (NICU). The system includes a plurality of microenvironments, a plurality of environmental sensors to detect a first environmental condition in the microenvironments, and a plurality of external environmental sensors to detect a second environmental condition in the NICU. The system also includes a central processor that compares signals from the environmental sensors to signals from the external environmental sensors and determines a correlation between the first environmental condition and the second environmental condition. A method of monitoring the conditions of a plurality of infants is also disclosed.

  • PEDIATRIC MONITOR SENSOR STEADY GAME

    A monitoring device for measuring one or more physiological parameters of a medical patient can include a finger clip sensor connected to a monitor. An accelerometer in the finger clip sensor detects patient motion or movement that may interfere with monitoring. In response, the monitor displays a message alerting the patient to stop moving or a game in which the objective requires the patient to hold his or her finger still. The device can delay measurement until the patient is still enough and remains still long enough for a clear measurement.

  • Pediatric Imaging Assembly

    A patient support assembly for use in a magnetic resonance image (MRI) scanner includes a first and a second patient support structure and a first and a second imaging coil. The patient support assembly provides support for multiple anatomical regions being imaged, improving patient comfort during the procedure. Access to the patient is improved by: providing a flexible coil that wraps around at least one of the anatomical regions being imaged, providing a support structure open to the anterior region of the anatomical region being imaged, and providing a support structure that may be opened and closed about the anatomical region being imaged. The patient support assembly also aligns the two imaging coils to minimize interference between coils during imaging.

  • PEDIATRIC NEBULIZER

    A nebulizer includes a body having an air channel section, medication reservoir and nebulizer outlet configured to be received within an oral cavity of a patient. A nebulizer suction member encloses the body and is configured as an infant pacifier. An air line extends through the air channel section and has a venturi nozzle and at its end configured to form a low pressure mixing chamber. A primary suction line extends from the medication reservoir to the low pressure mixing chamber through which medication is drawn upward and mixed with air passing through the venturi nozzle and nebulized for discharge through the nebulizer outlet.

  • NEW METHOD

    The invention provides a novel method of treating respiratory diseases, e.g., pediatric asthma, in a continuing regimen with not more than one daily dose of the drug budesonide using a nebulizer.

  • SYSTEM AND METHOD FOR MEASURING MID-ARM CIRCUMFERENCE OF A CHILD TO DETERMINE EQUIPMENT AND MEDICATION FOR PEDIATRIC RESUSCITATION

    Embodiments of the present invention are directed to a measuring tape for determining equipment sizes and medication dosages to use during the resuscitation of a pediatric patient. In one embodiment, the measuring tape may have a plurality of regions having different colors and/or patterns that identify weight zones that correlate with information and equipment required for resuscitating the pediatric patient. The measuring tape may be wrapped around the arm of the pediatric patient to determine the mid-arm circumference. Once wrapped around the arm, the color and/or pattern in alignment with an opening of the measuring tape may be used to identify a weight zone for the patient which provides the proper equipment size and medication dosages to be used for resuscitating the pediatric patient.

  • Formulations Containing an Ionic Mineral-Ion Exchange Resin Complex and Uses Thereof

    A process for preparing a formulation comprising a complex comprising an effective amount of ferrous iron bound to a pharmaceutically acceptable cationic resin and at least one pharmaceutically acceptable carrier is described. Such a formulation may optionally include other desirable dietary supplements including, e.g., vitamins, omega fatty acids, and/or fluoride. The formulation is particularly well adapted for pediatric use, but is also useful for use in adult populations.

  • SYSTEM AND METHOD FOR MEASURING MID-ARM CIRCUMFERENCE OF A CHILD TO DETERMINE EQUIPMENT AND MEDICATION FOR PEDIATRICRESUSCITATION

    Embodiments of the present invention are directed to a measuring tape for determining equipment sizes and medication dosages to use during the resuscitation of a pediatric patient. In one embodiment, the measuring tape may have a plurality of regions having different colors and/or patterns that identify weight zones that correlate with information and equipment required for resuscitating the pediatric patient. The measuring tape may be wrapped around the arm of the pediatric patient to determine the mid-arm circumference. Once wrapped around the arm, the color and/or pattern in alignment with an opening of the measuring tape may be used to identify a weight zone for the patient which provides the proper equipment size and medication dosages to be used for resuscitating the pediatric patient.

  • STABILIZED PEDIATRIC SUSPENSION OF CARISBAMATE

    The present invention provides a stabilized pharmaceutical suspension of carisbamate for pediatric and adult use. More particularly, the suspension is stabilized with hypromellose (HPMC) to prevent crystal growth of the suspended particles and to prevent re-crystallization of the drug product with change in polymorphic form.

  • Hinged Equinus Brace With Pediatric, Diabetic and Clubfoot Versions

    Devices and processes used to treat ankle equinus for users with specific conditions such as young age, diabetes, or clubfoot. More specifically, the present disclosure relates to a brace and the corresponding method of use to treat equinus by stretching the Gastrocnemius muscle.

  • SECURING DEVICE FOR TRANSPORT OF NEONATAL PATIENTS IN A TEMPERATURE-CONTROLLED INCUBATOR

    A securing device for transport of a neonatal patient in a temperature-controlled incubator comprises a vacuum mattress (12), comprising a gas-tight mattress case (14) enclosing a granular filler material (16), which vacuum mattress (12) is arranged to be brought from a flexible state into a rigid state by evacuation of gas from the same, the vacuum mattress (12) comprising a first side portion (28) arranged to be folded up around a first side of the patient (22), a second side portion (30) arranged to be folded up around a second side of the patient (22), and a bottom portion (27) arranged to be fastened in an incubator (48).

  • NEONATAL CRANIAL SUPPORT BONNET

    A neonatal cranial support bonnet is configured to prevent a premature child's head from deforming under the force of its own weight, because of underdeveloped cranial plates. The bonnet includes a thin cotton shell with contoured gel packs inside. The gel packs are configured to distribute weight around the skull and eliminate or reduce high-pressure points so as to maintain proper shape of the cranium. The bonnet is also configured to not interfere with development, and to not obstruct airways for breathing, so as to meet current Sudden Infant Death Syndrome prevention guidelines.

  • METHODS OF TREATING PEDIATRIC PATIENTS USING DEXMEDETOMIDINE

    The presently disclosed subject matter relates to methods of administering an effective amount of dexmedetomidine to a pediatric patient in order to reduce the incidence of neurological damage. More particularly, the presently disclosed subject matter relates to methods of providing sedation or analgesia to a pediatric patient by administering a dexmedetomidine infusion and optionally a loading dose. The dexmedetomidine can be administered before, during, or after surgery.

  • TRANSFORMABLE BED FOR EXAMINATIONS IN PEDIATRIC OPHTHALMOLOGY

    A transformable bed for examinations in pediatric ophthalmology, especially suitable for the use of general anesthesia when conducting eye examinations, is provided. The bed may include a fixed bed board, a movable bed board, a movable seat, a movable support, a securing strap, and a main frame. The bed may be fixedly connected to the top of the main frame, the movable bed board may be rotationally connected to the top of the main frame, and the movable seat may be rotationally connected to the top of the main frame. The securing strap may be disposed on the movable bed board, in which one end of the movable support may be removably connected to the movable bed board, and another end may be removably connected to the main frame. The transformable bed may function both as an anesthesia bed and a handcart, and may be quickly switched therebetween.

  • MICROCONTROLLER BASED PEDIATRIC DEVICE AND METHOD OF NOURISHMENT EVALUATION

    A microcontroller based breast milk flow meter and child milk volume intake detection and measuring method means comprising a silicone encapsulated flexible microcontroller circuit means with a plurality of on-board dielectric detector plate means and a piezo-resistive force sensor means. Where the dielectric detector plates function electrically, as a passive device means to determine the presence or absence of a quantity of milk in a holding chamber means and a piezo-resistive force sensor function electrically, as a passive device means to determine a continuous or sporadic flow quantity of milk from said chamber means. A special microcontroller algorithm is used to monitor, detect, and measure breast milk flow and quantity from mother to child.

  • NUTRITIONAL PHYTONUTRIENT COMPOSITIONS

    The present disclosure relates to milk-based nutritional compositions for pediatric subjects and to corresponding methods of using the nutritional compositions to promote health and development. The nutritional compositions comprise docosahexaenoic acid, choline and phytonutrients, such as apple extract, grape seed extract, or mixtures thereof. The nutritional compositions are believed to be useful in promoting visual health, gastrointestinal health, immune function and cognitive development and function in infants and children, and the compositions may be administered via a staged nutritional feeding regimen. The disclosure further relates to nutritional compositions that maintain desirable organoleptic properties after addition of phytonutrients to a milk-based matrix and still further relates to methods for producing the same.

  • NUTRITIONAL PHYTONUTRIENT COMPOSITIONS

    The present disclosure relates to milk-based nutritional compositions for pediatric subjects and to corresponding methods of using the nutritional compositions to promote health and development. The nutritional compositions comprise docosahexaenoic acid, choline and phytonutrients, such as apple extract, grape seed extract, or mixtures thereof. The nutritional compositions are believed to be useful in promoting visual health, gastrointestinal health, immune function and cognitive development and function in infants and children, and the compositions may be administered via a staged nutritional feeding regimen. The disclosure further relates to nutritional compositions that maintain desirable organoleptic properties after addition of phytonutrients to a milk-based matrix and still further relates to methods for producing the same.

  • COMPOSITION AND METHOD OF PHYTONUTRIENTS FOR METABOLIC PROGRAMMING EFFECTS

    The present disclosure relates methods of promoting phase II enzyme gene expression in a pediatric subject, comprising administering to the subject a nutritional composition comprising an effective amount of a phytonutrient. The disclosure also relates to methods of promoting phase II enzyme gene expression in a prenatal infant, comprising administering to a female pregnant with the prenatal infant an effective amount of a composition comprising phytonutrients. The disclosure further relates to a method of promoting phase II enzyme gene expression in a prenatal infant, comprising administering to a female pregnant with the prenatal infant an effective amount of a composition comprising phytonutrients.

  • METHODS BASED ON FLUCTUATIONS IN CORTICAL SYNCHRONIZATION

    The present disclosure relates methods of promoting phase II enzyme gene expression in a pediatric subject, comprising aA method of identifying a site of injury in a pediatric patient with brain injury is provided which comprises obtaining an electroencephalogram signal on the patient. The identification of phase synchrony within the signal is indicative of the site of brain injury. Electroencephalogram signals may also be used to determine prognosis of a pediatric patient in a coma in which an increase in the temporal variability of phase synchronized EEG signals over time is indicative of an improvement in the patient.dministering to the subject a nutritional composition comprising an effective amount of a phytonutrient. The disclosure also relates to methods of promoting phase II enzyme gene expression in a prenatal infant, comprising administering to a female pregnant with the prenatal infant an effective amount of a composition comprising phytonutrients. The disclosure further relates to a method of promoting phase II enzyme gene expression in a prenatal infant, comprising administering to a female pregnant with the prenatal infant an effective amount of a composition comprising phytonutrients.

  • COMPOSITION FOR PERINATAL AND NEONATAL STROKE

    The present invention relates to a novel, non-toxic, prophylactic maternal nutraceutical composition for prevention, treatment, minimization or amelioration of brain damage from perinatal and/or neonatal stroke.

  • System and Method of Neonatal Care

    An infant care system includes an infant care tower configured to receive at least one medical device. A processor operates the infant care tower and the at least one medical device. A bassinet is configured to receive an infant patient within a microenvironment defined and maintained by the bassinet. Upon connection of the bassinet to the infant care tower, the processor operates to control both the infant care tower and the bassinet in maintain the microenvironment of the bassinet. In a method of treating an infant patient, an infant patient is provided in a microenvironment defined and maintained by a bassinet. The bassinet is communicatively connected to the care tower and a first processor of the infant care tower operates the bassinet to maintain the microenvironment to provide medical care to the infant patient with the at least one medical device of the infant care tower.

  • Pediatric Esophageal Atresia Magnetic Anastomosis System

    A system and a method for joining an upper and lower esophageal sacs in an infant are provided. The system includes a first elongate member having a first magnet, the first magnet including an end portion configured to abut an interior surface of the upper esophageal sac. The system also includes a second elongate member having a second magnet, the second magnet including an end portion configured to abut an interior surface of the lower esophageal sac. The system further includes a third elongate member having a third magnet and a spacer positioned distal to the third magnet. The third elongate member is positionable in the upper esophageal sac after the first elongate member has been removed. A magnetic force between the first magnet and the second magnet is configured to pull the first magnet and the second magnet towards each other to lengthen the upper and lower esophageal sacs.

  • PEDIATRIC VISION TEST

    Disclosed are a method and kit for testing visual acuity in a subject. The examiner displays a test thread at a set distance in front of the subject's face, and then determines whether the subject grabs or looks at the test thread. These steps are repeated using subsequent threads of varying thickness. The smallest thread to which the subject responds is charted as their best VA in standard notation. The visual acuity of a young child can be quantified using standard adult Snellen acuity levels. The device can be used worldwide, as it transcends language barriers, and in a variety of practice settings, including pediatric ophthalmologist offices, general ophthalmologist offices, optometric offices, pediatricians and family doctors who see young children or persons unable to read a conventional Snellen chart and/or verbalize their responses.

  • COMPOSITION FOR INDUCING PLURIPOTENT STEM CELL, AND USE THEREOF

    The present invention provides Sendai virus vectors in which genes that encode reprograming factors for inducing pluripotent stem cells are incorporated in a specific order, compositions comprising these vectors for gene delivery to be used in the induction of pluripotent stem cells, and uses thereof. Incorporation of the KLF gene, OCT gene, and SOX gene in a specific order into a single Sendai virus vector successfully and significantly increased the efficiency of pluripotent stem cell induction. Loading multiple reprogramming factors into a single vector can further increase the induction efficiency of pluripotent stem cells while reducing the number of necessary vectors.

  • Differentiated Pluripotent Stem Cell Progeny Depleted of Extraneous Phenotypes

    The invention provides methods for depleting extraneous phenotypes from a mixed population of cells comprising the in vitro differentiated progeny of primate pluripotent stem cells. The invention also provides mixed cell populations enriched for a target cell phenotype where the mixed cell population comprises the differentiated in vitro progeny of primate embryonic stem cells.

  • COMPOSITIONS FOR PROMOTING HEMATOPOIETIC STEM CELL GROWTH

    The present invention provides for compositions and methods for modulating hematopoetic stem cell populations by using HCS modulators, which are agents that either increase HSC numbers or decrease HSC numbers as desired by a particular indication. For example, HSC modulators found to increase HSC numbers include prostaglandin E.sub.2 (PGE2) and agents that stimulate the PGE2 pathway. Conversely, HSC modulators that prevent PGE2 synthesis decrease HSC numbers. HCS modulators may be used in vitro, in vivo, or ex vivo.

  • METHOD FOR PROMOTING STEM CELL CHONDROGENESIS

    There is provided a method for promoting stem cell chondrogenesis, comprising the step of culturing a population of stem cells on a plurality of imprints disposed on a substrate, the imprints being configured to selectively promote chondrogenesis of the stem cells.

  • COMPOSITION FOR PREVENTING OR TREATING LIVER DISEASES, CONTAINING PLANT STEM CELL LINES DERIVED FROM THE CAMBIUM OF PANAX GINSENG INCLUDING MOUNTAIN GINSENG OR GINSENG AS ACTIVE INGREDIENT

    The present invention relates to a composition for preventing or treating liver diseases, which contains, as an active ingredient, any one or more of a homogeneous cell line derived from the cambium of Panax ginseng, including wild ginseng or ginseng, a lysate thereof, an extract thereof and a culture medium thereof. The homogeneous cell line according to the present invention, a lysate thereof, an extract thereof and a culture medium thereof have minimized side effects compared to existing agents for treating liver diseases, and thus are safe for the human body. Also, they can increase the levels of s-antibody (HBsAb) and e-antibody (HBeAb) against hepatitis virus and inhibit the proliferation of hepatitis virus, and thus they are useful for the prevention and treatment of liver diseases. In addition, they have the effect of lowering the levels of liver injury, and thus are useful as a functional food for improving liver function.

  • STEM CELL THERAPY USING INHIBITORS OF LYSOPHOSPHATIDIC ACID

    Methods are provided for stem cell therapy using inhibitors of lysophosphatidic acid (LPA). Inhibition of LPA may be direct or indirect; particularly preferred direct inhibitors of LPA are antibodies to LPA, including humanized monoclonal antibodies to LPA. Such inhibitors are used in combination with stem cells for the treatment of injuries, diseases, or conditions amenable to treatment by stem cell therapy.

  • Promoting Erythropoietin, Erythrocyte, and Hematopoietic Stem Cell Production By Activating HIF In OsteoBlasts

    Methods are provided for promoting the production of erythropoietin and the production of erythrocytes and hematopoietic stem and progenitor cells. These methods find us in the treatment of subjects with conditions in which erythrocyte cell numbers are reduced, for example, anemia, chronic kidney disease, and following chemotherapy treatment.

  • THERAPEUTIC IMMUNE MODULATION BY STEM CELL SECRETED EXOSOMES

    Disclosed are methods, compositions of matter, and protocols useful for the induction of a therapeutic immune modulatory response through administration of exosomes derived from a stem cell source. In one embodiment, said stem cell source is endometrial regenerative cells. Specifically, in one embodiment stem cell derived exosomes are used as a method of treating an autoimmune condition such as rheumatoid arthritis, multiple sclerosis, or systemic lupus erythromatosis.

  • MESENCHYMAL STEM CELL AND A METHOD OF USE THEREOF

    Demyelinated axons were remyelinated in the demyelinated rat model by collecting bone marrow cells from mouse bone marrow and transplanting the mononuclear cell fraction separated from these bone marrow cells.

  • MODULATION OF THE MAMMALIAN RECEPTOR mTOR TO INHIBIT STEM CELL DIFFERENTIATION INTO NEURONS

    The present application relates to compositions and methods for inhibiting the differentiation of isolated embryonic stem cells, induced pluripotent stem cells, parthenogentic stem cells, or isolated embryoid bodies into neuronal progenitor cells or neuron cells comprising a mTOR inhibitor and an effective amount of cell culture growth media. The mTOR inhibitor can be Rapamycin.

  • STEM CELLS AND METHODS FOR INCORPORATING ENVIRONMENTAL FACTORS AS A MEANS FOR ENHANCING STEM CELL PROLIFERATION AND PLASTICITY

    Disclosed are methods for expanding stem cells that use a unique combination of environmental factors and cell culture conditions to produce stem cells having enhanced proliferation and differentiation characteristics. Also disclosed are methods for enhancing the engraftment and/or migratory potential of stem cells for therapeutic uses. Stem cells having unique proliferation, differentiation, migratory and engraftment characteristics are also disclosed.

  • SELECTIVE INHIBITION OF BETA1- ADRENERGIC RECEPTORS FOR THE TREATMENT OF PEDIATRIC HEART FAILURE

    Provided are methods of treating heart failure in children using B1-selective adrenergic receptor antagonists, alone or in combination with other agents, including B-2-selective adrenergic receptor agonists.

  • Adjuvanted Influenza Vaccines for Pediatric Use

    An influenza vaccine adjuvanted with a sub-micron oil-in-water emulsion elicits significantly higher immune responses in human pediatric populations. Compared to an existing unadjuvanted pediatric influenza vaccine, the adjuvanted vaccines provided herein can induce in children a longer persistence of high serum antibody titers and also longer seroconversion and seroprotection. The improvement in immune responses is seen for both influenza A virus and influenza B virus strains, but it is particularly marked for influenza B virus. Moreover, while the existing vaccine provides poor immunity in children after a single dose, the adjuvanted vaccine provides high seroprotection rates against the influenza A virus H3N2 subtype even after a single dose. Furthermore, the adjuvanted vaccine offers significantly better seroprotection against mismatched strains of influenza A virus.

  • PATIENT CONTROLLED ANALGESIA FOR PEDIATRIC PATIENTS

    A method of providing a patient controlled analgesia to a pediatric patient including connecting a patient controlled analgesia system, such as an infusion pump and hand control, to an intravenous line of the pediatric patient and securing the hand control in a patient interface object, such as a stuffed toy having an internal void for receiving the hand control and an actuator affixed within the void. The patient is informed that pressing the area of the stuffed toy proximate to the actuator results in relieving pain experienced by the patient. Furthermore, an Internet address that is specific to the pediatric patient is provided to the patient for instructions on use of the combined patient controlled analgesia system and the patient interface object.

  • ANALYZING NEONATAL SALIVA AND READINESS TO FEED

    The present invention provides systems for assessing neonatal development and/or conditions by analyzing neonatal saliva RNA. Methods of identifying genes involved in neonatal development and/or conditions affecting neonates, are provided. Methods of determining a diagnosis of a neonate comprising detection of one or more differentially expressed genes are also provided.

  • METHODS OF TREATING PEDIATRIC METABOLIC SYNDROME

    In various embodiments, the present invention provides methods of treating and/or preventing pediatric metabolic syndrome comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.

  • METHODS OF TREATING PEDIATRIC PATIENTS USING DEXMEDETOMIDINE

    The presently disclosed subject matter relates to methods of administering an effective amount of dexmedetomidine to a pediatric patient in order to reduce the incidence of neurological damage. More particularly, the presently disclosed subject matter relates to methods of providing sedation or analgesia to a pediatric patient by administering a dexmedetomidine infusion and optionally a loading dose. The dexmedetomidine can be administered before, during, or after surgery.

  • MRI INVOLVING A LOCAL RF COIL BEING MOVABLE RELATIVE TO A PEDIATRIC PATIENT CARRIER

    A pediatric patient (110), e.g. 0-18 months, is positioned in a patient carrier (100) and prepared for magnetic resonance imaging. The carrier (100) and patient (110) are set on a patient support table (170) of the MRI scanner on which table a local RF coil assembly (180) has been mounted. The carrier (100) is slid along the table (170) into engagement with the RF coil assembly (180). Interacting guide surfaces on the carrier (100) and RF coil assembly (180) align the carrier (100) with a longitudinal axis of the table (170). The RF coil assembly (180) includes a pivotally mounted anterior coil (290) which is lowered into an imaging or operating position (400). The table with the engaged RF coil assembly (180), carrier (100) and pediatric patient (110) is translated into a magnetic imaging region (330) of the MRI scanner.

  • PEDIATRIC INTRAMEDULLARY NAIL

    Among other things, there are disclosed embodiments of an intramedullary nail system for use in pediatric cases, including an intramedullary nail and a targeting assembly. Embodiments of the nail may be one-piece and include a proximal portion, a medial portion and a distal portion. The junction of the medial portion and distal portion is a bend that provides a small angle between the medial portion and the distal portion as viewed when the nail is substantially in a medial-lateral plane. The targeting assembly attaches to the proximal portion of the nail securely and enables easy insertion of fixing screws.