The purpose of this investigation was to identify a best method for developing fast dissolving tablets (FDTs) of Naproxen sodium. Techniques like effervescent, superdisintegrants addition, sublimation were used. Different trails were designed and prepared. Effervescent agents citric acid and sodium bicarbonate; superdisintegrant crospovidone and subliming agent camphor were used for effervescent, superdisintegrants addition and sublimation methods respectively. The blend and compressed tablets were evaluated. The results showed that superdisintegrants addition method was the best one for formulating naproxen fast dissolving tablets.
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