Background: Adenosine 5ââ?¬â?¢-triphosphate (ATP) serves as a cellular source of energy for metabolic processes. Maintaining high levels of intracellular ATP has the potential to enhance performance. ElevATPââ??¢, a proprietary blend of ancient peat and apple extract, has twice been reported to increase intracellular blood levels of ATP in resting subjects after a single dose per os. More recently, resistance-trained males supplemented with ElevATPââ??¢ for 12 weeks, have shown increased resistancetraining- induced skeletal muscle hypertrophy. For this pilot study, we determined the acute effects of a single dose of ElevATPââ??¢ on the exercise output of subjects with sedentary lifestyles. Methods and findings: Nine healthy subjects were evaluated before, during, and after 20 minute duration stepping exercise in a blinded three-way crossover study of placebo and a single dose of ElevATPââ??¢. Two lots of ElevATPââ??¢ (Lot A and Lot B) were each compared to placebo in all subjects. Four (4) female and five (5) male subjects that did not regularly exercise were evaluated. Mean subject age was 27.3 Ã?± 5.0 years and BMI was 28.97 Ã?± 6.6 kg/mÃ?². ElevATPââ??¢ supplemented subjects (Lot A and Lot B) took a significantly greater number of steps and burned more calories than when treated with placebo. Post-exercise analysis has shown no significant changes in blood lactate or glucose levels between ElevATPââ??¢ (Lota A or Lot B) and placebo treatments. Conclusion: All nine subjects experienced an increase in exercise performance after ingesting a single dose of either of the two tested lots of ElevATPââ??¢, compared to a placebo control.
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