Chlorogenic acid (5-O-caffeoylquinic acid) is a phenolic compound from the hydroxycinnamic\nacid family. This polyphenol possesses many health-promoting properties, most of them related to the\ntreatment of metabolic syndrome, including anti-oxidant, anti-inflammatory, antilipidemic, antidiabetic,\nand antihypertensive activities. The first part of this review will discuss the role of chlorogenic acid\nas a nutraceutical for the prevention and treatment of metabolic syndrome and associated disorders,\nincluding in vivo studies, clinical trials, and mechanisms of action. The second part of the review\nwill be dealing with the role of chlorogenic acid as a food additive. Chlorogenic acid has shown\nantimicrobial activity against a wide range of organisms, including bacteria, yeasts, molds, viruses,\nand amoebas. These antimicrobial properties can be useful for the food industry in its constant search\nfor new and natural molecules for the preservation of food products. In addition, chlorogenic acid has\nantioxidant activity, particularly against lipid oxidation; protective properties against degradation\nof other bioactive compounds present in food, and prebiotic activity. The combination of these\nproperties makes chlorogenic acid an excellent candidate for the formulation of dietary supplements\nand functional foods.
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