Obesity and metabolic syndrome (MetS) are growing problems among children and adolescents. There are no reports of changes in\nthe activity of butyrylcholinesterase (BChE) in children and adolescents with metabolic syndrome especially after supplementation\nwith extract from Aronia melanocarpa. Materials studied included plasma and erythrocytes isolated from peripheral blood\nof patients with MetS and healthy subjects. We have estimated the following parameters: acetylcholinesterase (AChE) and\nbutyrylcholinesterase (BChE) activity, lipid peroxidation and lipids levels in plasma, and erythrocytes membrane. In patients\nwith MetS, a significant increase in AChE and BChE activity, higher LDL-cholesterol and triacylglycerol levels, and lower HDLcholesterol\nlevel were observed. Supplementation with A. melanocarpa extract resulted inmild but statistically significant reduction\nof total cholesterol, LDL-cholesterol, and triacylglycerol levels and caused an increase in HDL-cholesterol level and a decrease in\nlipid peroxidation in plasma patients withMetS. Additionally, a decrease in lipid peroxidation and cholesterol level and a decrease\nin AChE activity in the erythrocyte membranes after supplementation with A. melanocarpa were noted. Summarizing, an increase\nin AChE and BChE activity and disruption of lipid metabolism in patients with MetS were observed. After supplementation of\nMetS patients with A. melanocarpa extract, a decrease in AChE activity and oxidative stress was noted.
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