Vitamin D deficiency is frequent in the general population and both subjects and health\nprofessionals could benefit from a broader range of vitamin D3 formulations. We conducted a\nsingle-dose, open-label, parallel-group, randomized bioequivalence study to compare a single dose\nof a newly developed vitamin D3 100,000 IU in a soft capsule (Group 1) with the reference drug\nvitamin D3 100,000 IU oral solution in ampoule (Group 2) in healthy volunteers over a four-month\nperiod. The primary endpoint was the area under the curve (AUC) of serum 25-hydroxyvitamin-D\n(25(OH)D) concentrations on Day 112. This study was conducted in France from February to June\n2014 in 53 young adults with a mean age of 26.9 years. At baseline, low mean serum 25(OH)D levels\nwere observed in both groups (10.6 ng/mL in Group 1 and 9.0 ng/mL in Group 2). On Day 112,\nthe AUC of serum 25(OH)D concentration was..................
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