Widely prevalent deficiency of dietary fiber intake in daily food has led to widespread prevalence of absence of normal bowel movement and constipation. In response, instead of making up dietary fiber deficiency, paradoxically, non-food laxatives such as Psyllium husk, lactulose, maltitol, Ayurvedic medicines, other adjunctive medicines and similar laxatives are in wide use to overcome these problems. In general, high dietary foods have low palatability. LeFiber is a palatable high dietary fiber supplement to fulfill the deficiency of dietary fiber; which includes fiber of green leafy vegetable as one of the ingredients. The open label, double arm, prospective study to determine efficacy of 3•3 grams dietary fiber/dose given three times a day with food had normalizing bowel movements as primary end point and enriching gut flora in colon as indicated by Bifidobacteria as secondary outcome. In the clinical trial, this was compared to Psyllium husk as control in standard dose. This trial is registered with ClinicalTrials.gov No. CTRI no. CTRI/2018/04/13078. Results show that LeFiber is as effective as Psyllium husk in normalizing bowel movements. Longo score as Rome III Diagnostic Criteria for Functional Gastrointestinal Disorder- C3 was calculated. Mean Longo Score on day 0 for LeFiber was 9•03 from which the mean Longo Score decreased statistically significantly at P <0•0001 to 5•61 on day 7th, 1•42 at day 15th and 2•61 at day 30th. LeFiber enriched gut flora as indicated by increase in the number of Bifidobacteria which either declined or totally wiped out in the Psyllium husk arm.
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