Aging is a complex and inevitable biological process that is associated with numerous chronically debilitating health effects.\nDevelopment of effective interventions for promoting healthy aging is an active but challenging area of research. Mechanistic\nstudies in various model organisms, noticeably two invertebrates, Caenorhabditis elegans and Drosophila melanogaster, have\nidentified many genes and pathways as well as dietary interventions that modulate lifespan and healthspan. These studies have\nshed light on some of the mechanisms involved in aging processes and provide valuable guidance for developing efficacious aging\ninterventions. Nutraceuticals made from various plants contain a significant amount of phytochemicals with diverse biological\nactivities. Phytochemicals can modulate many signaling pathways that exert numerous health benefits, such as reducing cancer\nincidence and inflammation, and promoting healthy aging. In this paper, we outline the current progress in aging intervention\nstudies using nutraceuticals from an evolutionary perspective in invertebrate models.
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