The study was carried out to evaluate the effects of equine resveratrol supplement (equithrive jointTM) on\ninflammatory indices in ageing and lame horses. 16 horses of both sexes aged 18Ã?±0.65 years, showing lameness\ngrade 3 were used for the study. The horses weighed 350-450 kg and were randomly assigned to treated and\nuntreated groups comprising 8 horses each. Treated group were administered with resveratrol supplement for 4\nweeks while the untreated group were given only Saccharomyces cerevisiae yeast strain used as carrier in the\nsupplement. Blood samples were collected from each animal before supplementation on week 0 and then weekly for\nfour weeks of supplementation. Markers of inflammation consisting of tumour necrosis factor-alpha (TNFÃ?±),\nerythrocyte sedimentation rate (ESR), haematocrit level and serum protein concentration were determined by\nstandard methods. Equithrive joint TM supplementation reduced significantly (pÃ?â??0.05) the values of TNF-Ã?±\nconcentration, ESR and serum protein in the treated horses compare with the controls. The haematocrit level was\nsignificantly (pÃ?â??0.05) higher in treated horses compared with the controls. It was concluded that equithrive joint TM\nis a potent anti-inflammatory agent capable of reducing inflammatory mediators and thereby enabling horses move\nwith ease particularly during ageing.
Loading....