Background: This study examined the long-term effects of nurse-led, individualized education on self-efficacy, selfcare\ncompliance, and health-related quality of life (HRQoL) in middle-aged patients with new-onset acute coronary\nsyndrome.\nMethods: A quasi-experimental pretest-posttest design was used in the study. A cardiovascular nurse provided\nindividualized education to the intervention group (n = 32), and self-efficacy, self-care compliance, and HRQoL at\nbaseline and 3 and 12 months after discharge were compared to those of a control group (n = 30). Patients were\nrecruited from a cardiovascular care unit at a university hospital between 2012 and 2013. Repeated measures\nanalysis of variance was used to compare time-related changes.\nResults: There was no significant difference in self-efficacy between the 2 groups over a fixed period (F = 3.47,\np = 0.067) and showed no interaction between the 2 groups (F = 0.45, p = 0.636). However, significant differences\nwere found in the main and interaction effects between the 2 groups and changes in self-care compliance over the\nfollow-up period differed significantly between the 2 groups (F = 28.72, p < 0.001). Changes in mental HRQoL over\nthe follow-up period differed significantly between the 2 groups (F = 33.34, p < 0.001) and significant interaction\neffect (F = 4.40, p = 0.040).\nConclusions: Structured nurse-led education should be provided to middle-aged patients with new-onset acute\ncoronary syndrome, as part of routine predischarge education, to increase self-care compliance and mental HRQoL and\nprevent secondary adverse events.
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