The objective of the present investigation was to formulate and evaluate a nail lacquer as Transungual drug delivery system for the treatment of onychomycosis. Nail lacquer is formulated with DMSO and thioglycolic acid as penetration enhancers. Nail lacquer was evaluated for its drying time and non volatile content. In vitro drug permeation studies were carried out across nitrocellulose membrane using Franz diffusion cells. The % of drug permeated at the end of 3h through the membrane was calculated.
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