Tablets and Capsules are the conventional dosage forms administered through the oral route of drug delivery which is the conventional and oldest route of drug delivery. This conventional route of delivery has always been troublesome to the patients especially geriatrics, pediatrics and patients with cardiac problems. Scientists have always searched for an alternative to this conventional route. Intraoral route of drug delivery has been proved to be non-invasive and most preferred alternative to the conventional route of drug delivery. United States prove to be the best market for such fast dissolve dosage forms. Sublingual route is the most preferred route as compared to other intraoral routes for drug delivery due to lesser thickness of the mucosal membrane. Mucosal membrane is divided into Epithelium, lamina propia and submucosa. The absorption of drug across mucosal membranes takes place via two routes: paracellular route and transcellular route. Drug should follow various criteria for being suitable for sublingual delivery. Sublingual route has more advantages than disadvantages and is developing rapidly as preferred route for drug delivery.
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