In the modern day the mucoadhesive drug delivery systems have gained popularity for the various reasons. The highly permeable buccal mucosal membrane attracting many researchers to explore the possibilities administering drugs via buccal mucosa to get better bioavailability by avoiding first pass hepatic metabolism. Buccal dosage forms are mainly used to reduce the overall dose of drug and thus the dose related side effects can be reduced. Various dosage forms like tablets, films, patches, wafers, semisolid gels and lozenges are developed by using different mucoadhesive polymers. The dosage forms can be evaluated by properties like physical properties, mucoadhesive strength, tensile strength, swelling index, folding endurance, in-vitro drug diffusion and dissolution studies. Number of buccal formulations have been developed and are being marketed across the world.
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