A drug delivery system (DDS) is defined as a formulation or a device that enables the introduction of a therapeutic substance in the body and improves its efficacy and safety by controlling the rate, time and site of release of drugs in the body. Microsponges are porous, polymeric microspheres that are used mostly for topical and recently for oral administration. Many of conventional delivery systems require high concentrations of active agents to be incorporated for effective therapy because of their low efficiency as delivery systems. Thus, the need exists for delivery systems to maximize the period of time that an active ingredient is present, either on the skin surface or within the epidermis while minimizing its transdermal penetration into the body. Microsponge can be prepared by two different methods namely, (i) liquid- liquid Polymerization suspension method and (ii) quasi emulsification method. The microsponge technology delivers a wide range of applications in development of drug product and cosmetic product.
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