Malaria has remained a major public health concern in the developing world, caused by a protozoan parasite of the genus Plasmodium. More than 600 million people are infected annually resulting in more than three million deaths, mostly children in Africa. Increased resistance to malaria drugs has made the situation worse and control of the disease will require rapid development of new control methods, so development of vaccines against malaria is one of the most effective modes of treatment available. An effective vaccine against malaria that would protect non-immune individuals from the disease has long been a dream.
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