The objective of the present study is aiming at the novel methodologies in the development of Chronotherapy and designing accordingly to the chronological behavior of body. Although oral delivery has become a widely accepted route of administration of therapeutic drugs, the gastrointestinal tract presents several formidable barriers to drug delivery. The increasing research interest surrounding chronic drug delivery systems (ChrDDS) may lead to the creation of a new discipline in pharmaceutics known as chronopharmaceutics. Such novel and more biological approaches may lead to safer and more efficient disease therapy in future. This concept has several advantages, notably maximum therapeutic benefit, minimum harm, improved patient convenience and compliance. Pharmacists must realize the need to develop and dispense such medications having potential therapeutic benefit. The current article focuses on the diseases requiring pulsatile drug delivery system (PDDS), methodologies involved for the existing systems, recent update and PDDS products currently available in the market.
Loading....