Transdermal administration of drugs is generally limited by the barrier function of the skin. Vesicular systems are one of the most controversial methods for transdermal delivery of active substances. The interest in designing transdermal delivery systems was relaunched after the discovery of elastic vesicles: transferosomes and ethosomes. This paper presents the composition, manufacturing and characterization methods, mechanisms of penetration of transferosomes and ethosomes as transdermal delivery systems of active substances.
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