Herbo-mineral formulations of Ayurveda contain metals or minerals as composition, which have their beneficial effects on biological systems. These metals or minerals are transformed into non-toxic forms through various procedures explained in Ayurveda. Literature is available on composition of Vasantkusumakar Ras, Suvarnmalini Ras and Raupyasuvarn sutushekar Ras. The present document tries to analyze of chronic toxicity study of herbo-mineral compound in laboratory rats. Graded doses of Herbo-mineral compound Vasant kusumakar (higher dose 121.75 mg/kg p.o. lower dose 20.29 mg/kg p.o.), Suvarnmalini (higher dose 40. 58 mg/kg p.o. lower dose 20.29 mg/kg p.o.), Raupyasuvarn sutushekar (higher dose 40.58 mg/kg p.o lower dose 20.29 mg/kg p.o.) were administered daily to rats for 90 days and the effect on behavioral phenotype, body weight, water intake and histology were evaluated. The animal body weight and water intake significantly increased. Herbo-mineral compound showed non-toxic effect as indicated by its behavioral morphological and histopathological studies in wistar rats.
Loading....