Acacia catechu (Family Leguminose) is an important Indian medicinal plant, traditionally used to treat inflammations, skin diseases and urinary disorders, recommends its use as a blood purifier, in diseases caused by lipid disorders. Preliminary Phytochemical screening of the plant showed the presence of high amount of phenolics, tannins and alkaloids. High amount of tannins and phenolics prompted us to evaluate its antioxidant activity. We studied the antioxidant activity of Acacia catechu whole plant in three in vitro models: Anti-lipid peroxidation, Superoxide scavenging activity and measurement of reducing power. Ethyl acetate extract of Acacia catechu showed a very good Anti-lipidperoxidation activity (IC50- 47.71g/ml) compared with standard Ascorbic acid (IC50 -50.90 g/ml) and superoxide scavenging activity (IC50-29.88 g/ml) compared with Ascorbic acid (IC50-38.54g/ml) in a dose-dependent manner. The extract showed dose-dependent reduction ability (Fe3+ to Fe2+ transformation) with a maximum absorbance of 0.232 at a concentration of 80µg/ml of the extract.
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