The aim of present study was to investigate anticonvulsant effect of the ethanolic extract of leaves of Morringa olefera on electrically and chemically induced seizers. The for its anticonvulsant effect on maximal electroshock –induced seizers and pentylenetetrazole induced seizers .The latency of tonic convulsions and number of animals protected from tonic convulsions ware noted. Ethanolic extract of Moringa Oleifera Lam (200&400 mg /kg p.o.), Significantly reduced the duration of seizers induced by maximal electroshock (MES). However only 200 and 400 mg/kg of the extract confirmed protection (41.34% and 59.82% respectively) in pentylenetetrazole induced tonic seizers. It exert Anticonvulsant effect via non-specific mechanisms since it reduces the duration of tonic flexion, increases the duration of tonic extension, and increases the latency and onset of clonus of produced by maximal electroshock as well as delayed onset of death produced by pentylentetrazole.
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