momordica charantia Roxb fruit is most widely distributed through out India, Srilanka and other countries. The present study describes the anti-microbial activity of microwave-assisted extract of momordica charantia Roxb fruit against various Gram-positive and Gram- negative Microorganisms. For this purpose microwave-assisted extract of fruit were prepared and tested by “Disc Diffusion Method”. As a result of this study it was found that the microwave assisted extract of fruit generally revealed anti-microbial activity against both gram-positive bacteria (B. subtils, S. aureous and S.epidermis) and gram-negative bacteria (E. coli, S. flexineria and P. auriginosa).
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