Carbamazepine is an anticonvulsant drug. In the present work, a simple, sensitive, specific and validated method has been developed for the quantitative estimation of carbamazepine in bulk and pharmaceutical dosage form. Carbamazepine in the presence of acidic medium reacts with excess amount of chloramine-T and remaining chloramine-T reacts with crystal violet to produce a colour complex which shows absorption maxima at 596 nm. The linearity was found in concentration range of 10-50 μg/ml. The correlation coefficient was found to be 0.999. The method was validated as per USP and ICH guidelines.
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