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Inventi Rapid: Pharm Analysis & Quality Assurance

Articles

  • Inventi:prpaqa/16295/21
    A Validated UV Spectrophotometric Absorption Correction Method for Simultaneous Estimation of Diethylcarbamazine Citrate and Doxycycline Hydrochloride in their Synthetic Mixture
    01-Jul-2015 Research 2015 : July-September
    Chintankumar J Makwana*, Parth K Patel, Shreya R Shah, Grishma H Patel, Prasanna K Pradhan, Umesh M Upadhyay

    UV Spectrophotometric absorption correction method was developed for simultaneous estimation of diethylcarbamazine citrate (DEC) and doxycycline hydrochloride (DOXY) in their synthetic mixture. Wavelengths selected for application of method were 348 nm for DOXY and 209 nm for DEC and DOXY. Linearity was observed in concentration range of 6-42 µg/ml for DEC and 2-14 µg/ml for DOXY. Method was validated as per ICH Guidelines and found to be simple, precise and accurate. This method can be used for routine analysis.

    How to Cite this Article
    Chintankumar J Makwana, Parth K Patel, Shreya R Shah et al. A Validated UV Spectrophotometric Absorption Correction Method for Simultaneous Estimation of Diethylcarbamazine Citrate and Doxycycline Hydrochloride in their Synthetic Mixture. Inventi Rapid: Pharm Analysis & Quality Assurance, 2015(3):1-6, 2015.
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