Public hazard and health concerned with respect to sodium saccharin as artificial sweetener in various marketed routine products provoked us to perform present study, where a multitude of marketed products including mouthwash, toothpaste, antacid sachets, pan masala, supari, pan flavorings substances and sugar free cough syrup were collected from local market and analyzed. Analyzed samples were compared to maximum permissible limits for sodium saccharin content as approved by “fssai” for various products. This work represents chloroform based extraction method in marketed products followed by dissolving extract residue in 1% Na2CO3 and performing further dilution for UV analysis, similarly extract residue was dissolved in mobile phase (Acetonitrile: Phosphate buffer pH 3.5, 40:60% v/v) and analyzed by RP-HPLC after suitable dilution. Saccharin content was estimated using standard calibration curve of sodium saccharin, linearity range was found to be 10-50 μg/ml for both UV and HPLC method. Results showed many of samples to be falling out of fssai maximum permissible limit. Few sample showed Saccharin content without any label warning. The pharmacological study on sodium saccharin shows health hazard on long term intake hence marketed products had to be analyzed periodically for well being of individuals consuming sodium saccharin.
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