The aim of present work was to develop an accurate, simple and cost effective UV spectrophotometric method for estimation of metformin HCl. This method was based on area under curve of UV spectrum between 223-243 nm and validation as per ICH guideline Q2 (R1). The method has followed linearity in the range of 5-25 μg /ml. The value of correlation coefficient was 0.9993 satisfactory value of percent relative standard deviation for the intraday and inter-day precision indicates that method was precise. Result of the recovery studies (99.32) shows accuracy of method. The developed method can be used for routine estimation metformin HCl in bulk and dosage form.
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