A simple, precise, accurate and economical UV visible spectrophotometric method has been developed for estimation of perindopril erbumine and indapamide drug by AUC method. Quantitative determination of the drug was performed at wavelength range 208-214 nm and 239-244 nm for perindopril erbumine and indapamide respectively. The linearity was established over the concentration range of 10-50 µg/ml for perindopril erbumine and 1-5 µg/ml for indapamide with correlation coefficient value of 0.999 for both the drugs. Precision studies showed that % relative standard deviation was within range of acceptable limits. The recovery study was found to be within range of 99-101%. The proposed method has been validated as per ICH guidelines.
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