A novel, simple, precise and accurate area under curve spectroscopic method was developed and validated for the estimation of irbesartan in bulk and pharmaceutical dosage forms and AUC was measured at 202-212 nm in methanol and acetonitrile in ratio of 70:30. The linearity was found to be in the concentration range of 1-5 microgram/ml and the correlation coefficient was found to be 0.9991 and it has showed good linearity, reproducibility, precision in this concentration range. The regression equation was found to be Y=0.1163Ã?-0.007. The % recovery values were found to be within 98-100% showed that method was accurate. The LOD and LOQ were found to be 0.0273 and 0.08198 microgram/ml, respectively. The % RSD values were found less than 2. The developed method is accomplishing the validation parameters according to ICH guidelines. The developed method was successfully applied for the quantitative estimation of irbesartan in bulk and pharmaceutical dosage forms.
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