Atazanavir sulfate act as a protease inhibitor for the treatment HIV infection. Drug is of crucial importance to treatment and related research all over the world. So it is great interest of study to overview the analytical profile of ATV alone and in combination. The significant work is already reported for estimation of ATV. The privilege applicability of ATV was found by HPLC method and subsequently UV method. Very less literature was reported by UPLC and HPTLC methods. The ATV found in combination with ritonavir and cobicistat which are mostly used. The present article attempt to review many existing methodologies and the instrumental conditions that were applied in the last decade to quantify ATV and its metabolites. The authors have made special efforts to gather and compile the brand names of ATV alone and in combination. Such knowledge will assist in the development of new delivery systems in pharmaceutical research. The investigation will be useful and beneficial pre-formulation research and further analytical study of ATV.
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