Entacapone is a particular, reversible catechol methyl transferase (COMT) inhibitor for the treatment of Parkinson's ailment entacapone is a selective and reversible inhibitor of catechol ortho methyltransferase (COMT), with essentially fringe actions. It is utilized in the treatment of Parkinson's malady as an extra to levodopa/carbidopa treatment. So it is extraordinary enthusiasm of study to outlines the investigative profile of ETP alone and in mix. The benefit relevance of ETP was found by HPLC technique and in this manner UV strategy. Less writing was accounted for by UPLC and LC MS-MS strategies. Such estimations consistently need exact pharmacological and physicochemical data; subsequently creators have introduced it in advance. The article further presents a concurrent and similar appraisal of the diagnostic investigations referencing pharmaceutical estimation of medication to aid current examination. The careful writing look through uncovered twenty five research papers altogether till date. Such information will aid the advancement of new conveyance frameworks in pharmaceutical research.
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