A simple, sensitive, accurate, precise, reproducible and cost effective UV spectroscopic method has been developed for the estimation of Diacerein in bulk form. Diacerein shows maximum absorption at 258 nm with molar absorptivity of 2.9682 × 104 l/mol.cm. Beer’s law was obeyed in the concentration range of 1-25 µg/ml. The method was validated for linearity, precision, accuracy, sensitivity and specificity. The data obtained was treated with the statistical approach. The proposed method was not only found to be accurate and precise for estimation of Diacerein in bulk drug substance. During method development priority was given to using environment-friendly chemicals.
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