A new, simple, rapid and novel simultaneous equation method has been developed & validated for simultaneous estimation of Citicoline and Piracetam in their combined tablet dosage form. The method involves measurement of absorbance at two wavelengths, 216 nm and 275 nm λmaxof Piracetam and Citicoline respectively. Beer’s law obeyed in concentration range of 32-72 μg ml-1 and 40-90 μg ml-1 for Piracetam and Citicoline respectively. The method was found to be precise, accurate and specific by statistical parameters and recovery studies. The proposed method was successfully applied for Simultaneous estimation of Citicoline and Piracetam in combined solid dosage form.
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