A simple, rapid, sensitive and accurate RP-HPLC method has been developed for estimation of Fluconazole and Ivermectin in bulk drug and in pharmaceutical formulation. Linearity was observed in the concentration range of 100-300 μg/ml and 4-12 μg/ml for Fluconazole (r2 =0.998) and Ivermectin (r2 =0.997) respectively. Amounts of drug estimated from tablet formulation were in good agreement with label claim. The method was validated statistically and by recovery studies. The proposed method is economical and sensitive for the estimation of Fluconazole and Ivermectin in bulk and tablet dosage form.
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