Inflammation is a protective immune response against harmful stimuli whose long time continuation results in host disease. Quinazolinones are nitrogen containing heterocyclic compounds with wide spectrum of biological activities. The present review focuses on the Quinazolinone derivatives with potential anti inflammatory activity that are now in development. In recent year heterocyclic compounds analogues and derivatives have attracted strong interest due to their useful biological and pharmacological properties. When one biological active molecule is linked to another, resultant molecule generally has increased potency. Based on the literature review, the biological profiles of these new generations of Quinazolinone derivatives represent much progress with regards to older compounds.
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