A series of novel 2-[5-Mercapto-3-(4-substituted-phenyl)-[1,2,4]triazol-4-yl]- phthalamic acid derivatives were synthesized from various 4-Amino -5-mercapto-3-(substituted phenyl)-1, 2, 4-triazole derivatives by conventional and microwave method. The structures of final synthesized compounds were confirmed by using FT-IR, 1HNMR, LC-MS. All the synthesized compounds were screened for their in-vitro antibacterial activities against six bacterial strains using the agar disc-diffusion. A significant level of activity was observed.
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