Hyperlipidemia is a major risk factor for atherosclerosis. In animal models ethanol, propylthiouracil, high fat diet and CCT diet are used to produces hyperlipidemia. Ehanol replaces fat as asource of energy and increases total cholesterol level. Propylthiouracil produce hypothyroidism and hyperlipidemia. In high fat diet and CCT diet both are increase the total cholesterol level by their components. Ethanol and propylthiouracil less affect the total cholesterol level as compared to high fat diet. CCT diet more increase total cholesterol level as compared to high fat diet.
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