To study the purgative activity of Thalictrum foliolosum DC root extracts. The crude aqueous and alcoholic extracts of Thalictrum foliolosum roots were investigated for its purgative activity by Capasso et al. method in rat at doses of 200 mg/kg and 400 mg/kg, orally that was compared with castor oil as standard drug. The aqueous extract of root produce significant (P<0.05) purgative activity in dose dependent manner when compared with castor oil. The extracts showed purgative activity at 200 mg/kg and 400 mg/kg and were comparable with castor oil. The crude aqueous and alcoholic extracts show significant purgative activity at both doses when compared with standard drug castor oil (1 ml/kg).
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