It is demonstrated that the efficiency of antibiotics can be tested using an interferometric method. Two antibiotics were used as\r\nmodels to show that an interferometric method to monitor the metabolic activity of slowly growing bacteria can be a safer method\r\nto judge antimicrobial properties of substances than conventional methods. The susceptibility of Mycobacterium bovis to hexane\r\nextract of Pterodon emarginatus and to the well-known antibiotic rifampicin was tested with the interferometric method and\r\nwith the conventional microplate method. The microplate method revealed a potential activity of hexane extract against M. bovis.\r\nHowever, the interferometric method showed that the action of this substance is rather limited. Also in the case of rifampicin, the\r\ninterferometric method was able to detect resistant bacteria.
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