Diabetes mellitus often simply referred to as diabetes—is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. This high blood sugar produces the classical symptoms of polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger). The present study was undertaken to monitor the effect of aspirin on heart rate variability in diabetes. The present study involves Grouping 30 animals (Wistar Rats Female) in 4 different groups such as-Normo-Glycemic Group(A), Diabetic Control Group(B), Standard Group(C), Test Group(D) (n= 6, per each group). Diabetes was induced in Group B, Group C and Group D with alloxan (100 mg/kg, i.p). Blood Sugar level was checked for confirmation of induction of diabetes initially after 3 days and also at 7 days interval (ERBA). Aspirin proved to be successful in controlling the heart rate downfalls observed in diabetes. The results are supported by the ECG. Also, the plot of heart rate against time with the values obtained during the course of study suggests the usefulness of aspirin in diabetics.
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