The aim of the study is to evaluate the effectiveness of Structured Teaching Programme on knowledge regarding Substance abuse among Young adults in a selected College of Nursing at Kollam district. The objectives of the study were to assess the knowledge regarding Substance Abuse, to evaluate the effectiveness of Structured Teaching Programme on knowledge regarding Substance Abuse and to find out the association between pretest knowledge scores with the socio demographic variables. A quantitative research approach was employed for the research study. The study was undertaken with 63 subjects by using Convenience sampling technique. The tool was developed and the content validity and reliability of the tool were assessed. The research design was one group pretest posttest design. Structured Knowledge Questionnaire was used for collecting data. Pretest was administered followed by structured teaching programme and posttest was done. The result showed that average scores of knowledge before and after Structured Teaching Program in the subjects were 10.28 and 15.25 respectively. The computed 't' value of knowledge regarding Substance abuse was 15.86 with p value of 0.0001 and it was significant at 0.05 level (p<0.05). The findings showed that there was a significant improvement in the posttest knowledge level of first semester nursing students.
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