Nanosuspensions have emerged as a promising strategy for the efficient delivery of drugs because of their versatile features and unique advantages. Nanosuspensions are colloidal dispersions and biphasic system consisting of drug particles dispersed in an aqueous vehicle in which the diameter of the suspended particle is less than 1 μm in size. Reduction of drug particles to nanometer range leads to an enhanced dissolution rate due to increased surface area and saturation solubility. The formulation of nanosuspension includes stabilizer, polymer, organic solvent, co-surfactant, drugs and other additives. Nanosuspension can be prepared by various methods like top-down methods, bottom-up methods and methods employing combinatorial approaches etc. The electrostatic repulsion and steric stabilization are the two theories behind the formulation of nanosuspension. This review article describes the methods and characterization of the Nanosuspension.
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