This study aimed to develop a carbamazepine (CBZ) sustained release formulation suitable\nfor pediatric use with a lower risk of precipitation. The CBZ was first prepared as sustained\nrelease microparticles, and then the microparticles were embedded in alginate beads, and finally, the\nbeads were suspended in a gel vehicle. The microparticles were prepared by a solvent evaporation\nmethod utilizing ethyl cellulose as a sustained release polymer and were evaluated for particle size,\nencapsulation efficiency, and release profile. The beads were fabricated by the dropwise addition of\nsodium alginate in calcium chloride solution and characterized for size, shape, and release properties.\nThe gel was prepared using iota carrageenan as the gelling agent and evaluated for appearance,\nsyneresis, drug content uniformity, rheology, release profile, and stability. The microparticles exhibited\na particle size of���������..
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